Emerging data supporting stromal cell therapeutic potential in cancer: reprogramming stromal cells of the tumor microenvironment for anti-cancer effects.

AH Nwabo Kamdje, PF Seke Etet… - Cancer Biology & …, 2020 - search.ebscohost.com
… protein (YAP)-mediated lipogenesis reprogramming56, further … : conferring survival advantage
to breast cancer stem cells … interaction with human mesenchymal stroma/stem-like cells (…

[HTML][HTML] The role of PPARs in breast cancer

B Zhao, Z Xin, P Ren, H Wu - Cells, 2022 - mdpi.com
Breast cancer is a malignant tumor with high morbidity and … box) boxes, which confer
heterodimerization and PPARs DNA … the expression of the lipogenic genes in hepatocytes and …

Lipid Metabolic Reprogramming: Implications in Development of Cancer Drug Resistance and Nonalcoholic Fatty Liver Disease

WW Feng - 2020 - search.proquest.com
… T2DM symptoms in diabetics may confer additional benefits. However, the mechanism of …
of cancer cells upon endogenous lipogenesis. Because rBT474 cells exhibit an increased

[HTML][HTML] Pharmacological basis and new insights of taxifolin: A comprehensive review

A Das, R Baidya, T Chakraborty, AK Samanta… - Biomedicine & …, 2021 - Elsevier
… Along with that it is also found in conifers like the Siberian larch, … proliferation of the cancer
cells required high lipogenesis and glucose … that contains the stem like properties. These stem …

[HTML][HTML] Inflammation-induced tumorigenesis and metastasis

S Hibino, T Kawazoe, H Kasahara, S Itoh… - International journal of …, 2021 - mdpi.com
… a role in the survival of cancer stem-like cells in breast cancer [278,… cellular growth signaling,
such as JAK2, confer resistance to environmental stress and enhance survival advantages […

[HTML][HTML] Effects of dietary intervention on human diseases: molecular mechanisms and therapeutic potential

YL Xiao, Y Gong, YJ Qi, ZM Shao… - Signal Transduction and …, 2024 - nature.com
… as yogurt—may confer protective effects against … cells (Tregs) is increased, and these cells
adapt to high-LA conditions. Furthermore, cancer cells can take advantage of immune cells

Regulation of Energy Metabolism in Extracellular Matrix Detached Breast Cancer Cells

MP Sheeley - 2021 - search.proquest.com
… Wnt and Notch signaling induces a mesenchymal stem-like … to confer anoikis resistance,
demonstrated when increased … In adipose tissue PC activity primarily contributes to lipogenesis, …

[HTML][HTML] Aspects of the tumor microenvironment involved in immune resistance and drug resistance

K Khalaf, D Hana, JTT Chou, C Singh… - Frontiers in …, 2021 - frontiersin.org
… to stem-like cells was observed in a study of breast cancer cellsHigh lactate content promotes
survival of hypoxic cells by … High lipogenic enzyme concentration is correlated to invasion …

Targeting metabolic vulnerabilities driven by RON expression in recurrent/progressive breast cancer

BG Hunt - 2022 - search.proquest.com
… fertile offspring and show a survival advantage over RON-/mice … to confer tamoxifen resistance
in breast cancer cells and … supports breast cancer stem-like/tumor-initiating cell properties …

[HTML][HTML] RORγ is a context-specific master regulator of cholesterol biosynthesis and an emerging therapeutic target in cancer and autoimmune diseases

H Zou, N Yang, X Zhang, HW Chen - Biochemical Pharmacology, 2022 - Elsevier
… without showing consistent benefits to cancer patients. Nuclear … forms lipid rafts, which
confers important cellular signaling [2]. It … activate lipogenesis through activation of SREBP1 [81]. …