[HTML][HTML] Emergence of genetically linked vaccine-originated poliovirus type 2 in the absence of oral polio vaccine, Jerusalem, April to July 2022
NS Zuckerman, I Bar-Or, D Sofer, E Bucris… - …, 2022 - eurosurveillance.org
NS Zuckerman, I Bar-Or, D Sofer, E Bucris, H Morad, LM Shulman, N Levi, L Weiss…
Eurosurveillance, 2022•eurosurveillance.orgWe report an emergence and increase in poliovirus type 2 detection via routine wastewater
surveillance in three non-overlapping regions in the Jerusalem region, Israel, between April
and July 2022. Sequencing showed genetic linkage among isolates and accumulation of
mutations over time, with two isolates defined as vaccine-derived polioviruses (VDPV). This
demonstrates the emergence and potential circulation of type 2 VDPV in a high-income
country with high vaccine coverage and underscores the importance of routine wastewater …
surveillance in three non-overlapping regions in the Jerusalem region, Israel, between April
and July 2022. Sequencing showed genetic linkage among isolates and accumulation of
mutations over time, with two isolates defined as vaccine-derived polioviruses (VDPV). This
demonstrates the emergence and potential circulation of type 2 VDPV in a high-income
country with high vaccine coverage and underscores the importance of routine wastewater …
We report an emergence and increase in poliovirus type 2 detection via routine wastewater surveillance in three non-overlapping regions in the Jerusalem region, Israel, between April and July 2022. Sequencing showed genetic linkage among isolates and accumulation of mutations over time, with two isolates defined as vaccine-derived polioviruses (VDPV). This demonstrates the emergence and potential circulation of type 2 VDPV in a high-income country with high vaccine coverage and underscores the importance of routine wastewater surveillance during the polio eradication.
eurosurveillance.org
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