A review on iron chelators as potential therapeutic agents for the treatment of Alzheimer's and Parkinson's diseases
… Therefore, the development of novel iron chelators as neuroprotective agents for the
treatment of neurodegeneration is an emerging trend. Several iron chelators including 8-…
treatment of neurodegeneration is an emerging trend. Several iron chelators including 8-…
The role of manganese dysregulation in neurological disease: emerging evidence
D Budinger, S Barral, AKS Soo, MA Kurian - The Lancet Neurology, 2021 - thelancet.com
… Moreover, manganese dyshomoeostasis is also implicated in Parkinson's disease and
other neurodegenerative conditions, such as Alzheimer's disease and Huntington's disease. …
other neurodegenerative conditions, such as Alzheimer's disease and Huntington's disease. …
Pesticides and Parkinson's disease: Current and future perspective
… Cell therapy is also an emerging and promising technology for disease modeling and drug
… have suggested a correlation of pesticides and Parkinson's disease (PD) while genetic and …
… have suggested a correlation of pesticides and Parkinson's disease (PD) while genetic and …
The understanding of Parkinson's disease through genetics and new therapies
O Uwishema, H Onyeaka, R Badri, AN Yücel… - Brain and …, 2022 - Wiley Online Library
… Nowadays, it is well known that the cause behind Parkinson's disease is mainly … ,
factors causing Parkinson's disease as well as future therapies for the cure of the diseases. …
factors causing Parkinson's disease as well as future therapies for the cure of the diseases. …
[HTML][HTML] Emerging role of Sirtuin 2 in Parkinson's disease
Y Liu, Y Zhang, K Zhu, S Chi, C Wang… - Frontiers in aging …, 2020 - frontiersin.org
… Parkinson’s disease (PD) is one of the most common neurodegenerative diseases and is
characterized by the loss of dopaminergic (DA) neurons in the striatum and the aggregation of …
characterized by the loss of dopaminergic (DA) neurons in the striatum and the aggregation of …
PARP inhibitors and Parkinson's disease
AL Olsen, MB Feany - New England Journal of Medicine, 2019 - Mass Medical Soc
… Drug repurposing has emerged as a promising therapeutic strategy to reduce the costs and
safety failures associated with the development of new drugs. … Finally, there is emerging …
safety failures associated with the development of new drugs. … Finally, there is emerging …
[HTML][HTML] Historical perspective: models of Parkinson's disease
SJ Chia, EK Tan, YX Chao - International journal of molecular sciences, 2020 - mdpi.com
… Moreover, cell-based model has also emerged as a feasible disease model for PD. There
are distinct advantages and limitations of each group which determine the suitability of the …
are distinct advantages and limitations of each group which determine the suitability of the …
Neuroprotective actions of glucagon-like peptide-1 (GLP-1) analogues in Alzheimer's and Parkinson's diseases
… The current review provides a synthesis of emerging links between insulin resistance and
the pathogenesis of AD and PD and discusses the basis for investigation of antidiabetic agents…
the pathogenesis of AD and PD and discusses the basis for investigation of antidiabetic agents…
[HTML][HTML] Modifiable risk and protective factors in disease development, progression and clinical subtypes of Parkinson's disease: What do prospective studies suggest …
D Belvisi, R Pellicciari, G Fabbrini, M Tinazzi… - … of disease, 2020 - Elsevier
… In conclusion, the findings that emerged from prospective studies designed to investigate
the dietary intake of calories, carbohydrates, proteins, and cholesterol excluded a strong …
the dietary intake of calories, carbohydrates, proteins, and cholesterol excluded a strong …
[HTML][HTML] Role of exosomes in the pathogenesis of inflammation in Parkinson's disease
KL Li, HY Huang, H Ren, XL Yang - Neural Regeneration …, 2022 - journals.lww.com
Inflammatory responses, including glial cell activation and peripheral immune cell infiltration,
are involved in the pathogenesis of Parkinson’s disease (PD). These inflammatory …
are involved in the pathogenesis of Parkinson’s disease (PD). These inflammatory …