The role of microRNA-21 in the onset and progression of cancer

A Singh, AK Singh, R Giri, D Kumar… - Future medicinal …, 2021 - Taylor & Francis
… miR-21 regulation in cancer cells Almost all cancer cells show a common genetic marker –
microRNA-21. Overexpression of this miRNA is correlated with oncogenesis. Comparison of …

The role of microRNA-21 (miR-21) in pathogenesis, diagnosis, and prognosis of gastrointestinal cancers: A review

BF Far, K Vakili, M Fathi, S Yaghoobpoor, M Bhia… - Life sciences, 2023 - Elsevier
… could be a new diagnostic or … role of miR-21 in many other pathways involved in cancer
progression. Even though miR-21 has been related to the prognosis of gastrointestinal cancers, …

Dissecting the functional role of microRNA 21 in osteosarcoma

D Sekar, P Mani, M Biruntha, P Sivagurunathan… - Cancer gene …, 2019 - nature.com
microRNA 21 (miR-21) is considered to be a trivial marker for many diseases and has
been upregulated in many cancers. Moreover, it plays a main role in proliferation, migration, …

From molecular mechanisms to therapeutics: understanding MicroRNA-21 in cancer

J Rhim, W Baek, Y Seo, JH Kim - Cells, 2022 - mdpi.com
MicroRNA-21 and Its Role in Cancer Among the many miRNAs that have been associated
with cancer progression, microRNA-21 (miR-21) was among the first to be identified as an …

Critical role of microRNA-21 in the pathogenesis of liver diseases

T Zhang, Z Yang, P Kusumanchi, S Han… - Frontiers in …, 2020 - frontiersin.org
… (44) revealed a new role for miR-21 in hepatocytes in promoting hepatic insulin resistance
and steatosis in diet-induced obese mice through regulation of forkhead box protein O1 (…

MicroRNA 21 emerging role in diabetic complications: a critical update

D Roy, A Modi, M Khokhar… - Current diabetes …, 2021 - ingentaconnect.com
… have emerged as possible biomarkers by virtue of their presence in biological fluids in easily
accessible forms [2, 6]. Among these, microRNA-21 (miR-21) is said to play a pivotal role in …

Diagnostic, prognostic, and therapeutic potency of microRNA 21 in the pathogenesis of colon cancer, current status and prospective

A Bahreyni, M Rezaei, A Bahrami… - Journal of Cellular …, 2019 - Wiley Online Library
… Clinical value of microRNA 21 in the pathogenesis of colon cancer. CRC, colorectal cancer
[… , and of especial interest in this review in colorectal carcinoma (Chan, Krichevsky, & Kosik, …

The prognostic value of small noncoding microRNA-21 expression in the survival of cancer patients: a meta-analysis

MM Binabaj, A Bahrami, M Khazaei… - Critical Reviews™ in …, 2020 - dl.begellhouse.com
… of miR-21 in cancer progression is controversial. This meta-analysis includes 76 studies of
10,213 cancer patients to test miR-21 prognostic value in various human cancers. We obtain …

The diagnostic role of microRNA 21 in patients with nonsmall cell lung cancer: An exploratory study

S Rai, PK Garg, S Bhatt, TK Latha, AK Verma… - Lung India, 2020 - journals.lww.com
… A receiver operating curve displays the diagnostic value of serum microRNA 21 with the
diagnosis of nonsmall cell lung cancer area under curve of 0.84 (95% confidence interval of 0.74…

microRNA-21 promotes breast cancer proliferation and metastasis by targeting LZTFL1

H Wang, Z Tan, H Hu, H Liu, T Wu, C Zheng, X Wang… - BMC cancer, 2019 - Springer
… As microRNAs play vital role in breast cancer, this study aimed to explore the molecular …
the EMT in several cancers [35]. In our study, we will explore the new target gene of miR-21 and …