Protection of kidney function and tissue integrity by pharmacologic use of natriuretic peptides and neprilysin inhibitors
J Brignone, KB Assersen, M Jensen, BL Jensen… - … -European Journal of …, 2021 - Springer
… , likely through efferent arteriolar vasoconstriction, lowers renal plasma flow. Vasa recta …
volume and increases activity in the renin-angiotensin system, which will have effects in the …
volume and increases activity in the renin-angiotensin system, which will have effects in the …
ACE-Inhibitors in Hypertension: A historical perspective and current insights
S Cutrell, IS Alhomoud, A Mehta, AH Talasaz… - Current Hypertension …, 2023 - Springer
… heart failure and chronic kidney disease. These agents … II causes arterial and venous
vasodilation, natriuresis, and a … with ACE inhibitors, the mechanism of ACE inhibitor-induced …
vasodilation, natriuresis, and a … with ACE inhibitors, the mechanism of ACE inhibitor-induced …
Renal and vascular effects of combined SGLT2 and angiotensin-converting enzyme inhibition
Y Lytvyn, K Kimura, N Peter, V Lai, J Tse, L Cham… - Circulation, 2022 - Am Heart Assoc
… inhibition and efferent vasodilation with ACE inhibition … blood pressure without affecting
natriuresis or volume status. In … on albuminuria because of the low burden of kidney disease; …
natriuresis or volume status. In … on albuminuria because of the low burden of kidney disease; …
The renin‐angiotensin‐aldosterone system and its suppression
MK Ames, CE Atkins, B Pitt - Journal of veterinary internal …, 2019 - Wiley Online Library
… enzymes that lead to a pressure natriuresis.102-104 This allows the kidney to “escape” from
… ) to an established angiotensin converting enzyme inhibitor (ACEI), enalapril (dashed line), …
… ) to an established angiotensin converting enzyme inhibitor (ACEI), enalapril (dashed line), …
Critical role of neprilysin in kidney angiotensin metabolism
CC Kaltenecker, O Domenig, C Kopecky… - Circulation …, 2020 - Am Heart Assoc
… kidney and patients with chronic kidney disease (CKD).A, … of NEP inhibitor and ACE inhibitor
or ACE2 inhibitor (MLN-… several endogenous peptides with natriuretic-, vasodilatory-, and …
or ACE2 inhibitor (MLN-… several endogenous peptides with natriuretic-, vasodilatory-, and …
The Kidney in Hypertension
E Wühl, F Schaefer - Hypertension in Children and Adolescents: New …, 2019 - Springer
… of angiotensin II on vascular tone and renal tubular sodium reabsorption. Natriuretic peptides
are degraded in the lung and kidney by … ACE inhibitor treatment, but not calcium channel …
are degraded in the lung and kidney by … ACE inhibitor treatment, but not calcium channel …
[HTML][HTML] Potential effects and application prospect of angiotensin receptor-neprilysin inhibitor in diabetic kidney disease
X Zhang, Y Zhou, R Ma - Journal of Diabetes and its Complications, 2022 - Elsevier
… natriuretic peptide (BNP) and C-type natriuretic peptide (CNP), participates in fluid balance
by natriuresis and vasodilation… (UACR) compared with enalapril. A retrospective cohort study …
by natriuresis and vasodilation… (UACR) compared with enalapril. A retrospective cohort study …
Natriuretic peptides and neprilysin inhibition in hypertension and hypertensive organ damage
J Kato - Peptides, 2020 - Elsevier
… actions including natriuresis and vasodilatation by binding to … , such as inhibition of the
renin-angiotensin or sympathetic … the kidneys target organs of hypertension, but impaired renal …
renin-angiotensin or sympathetic … the kidneys target organs of hypertension, but impaired renal …
The combination of a neprilysin inhibitor (sacubitril) and angiotensin-II receptor blocker (valsartan) attenuates glomerular and tubular injury in the Zucker Obese rat
J Habibi, AR Aroor, NA Das… - Cardiovascular …, 2019 - Springer
… of an inhibitor of neprilysin (sacubitril), a natriuretic peptide-… of kidney injury involves
administration of angiotensin-… of decline in eGFR compared to enalapril and this positive result …
administration of angiotensin-… of decline in eGFR compared to enalapril and this positive result …
Angiotensin receptors in the kidney and vasculature in hypertension and kidney disease
… the formation of angiotensin (Ang) II, angiotensin-converting enzyme inhibitors (ACEIs) and
… R knockout mice have a lower threshold for pressure natriuresis as well as a reduction in net …
… R knockout mice have a lower threshold for pressure natriuresis as well as a reduction in net …