An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles

BC Evans, RB Fletcher, KV Kilchrist, EA Dailing… - Nature …, 2019 - nature.com
penetrating peptides/protein transduction domains that are … gold based hybrid nanoparticles,
and the use of cell penetrating … utilizing a gold nanoparticle conjugated to cationic polymers …

Prospect of cell penetrating peptides in stem cell tracking

X Zhang, T Lei, H Du - Stem Cell Research & Therapy, 2021 - Springer
… complex is mainly limited to endocytosis, but the TAT/small peptide complex is internalized
by … [90] designed a cell penetrating peptide (TAT)-conjugated, porous silicon nanoparticle (…

Recent advances in selective and targeted drug/gene delivery systems using cell-penetrating peptides

SH Nam, J Park, H Koo - Archives of Pharmacal Research, 2023 - Springer
… Bypassing endocytosis allows the CPP-based delivery systems greater … conjugated to the
MMP9 substrate peptide (PLGLAGGC) linked to TAT and used as a shell of PTX nanoparticles. …

[HTML][HTML] Overcoming the cellular barriers and beyond: Recent progress on cell penetrating peptide modified nanomedicine in combating physiological and …

Y Liu, Z Zhao, M Li - Asian Journal of Pharmaceutical Sciences, 2022 - Elsevier
conjugation of CPPs with nano-drug delivery systems. The applications of CPP-modified
nanoparticles (… direct penetration and energy-dependent endocytosis. Direct penetration is an …

CellPenetrating PeptideConjugated Polymer Micelle for pDNA/siRNA Delivery

T Kanazawa - CellPenetrating Peptides: Design …, 2023 - Wiley Online Library
… , nucleotides, and nanoparticles such as liposomes and polymer micelles by endocytosis
[7–… ), could transport siRNA inside the cell and mediate silencing directly proportional to the …

Cell-penetrating mechanism of intracellular targeting albumin: contribution of macropinocytosis induction and endosomal escape

S Ichimizu, H Watanabe, H Maeda, K Hamasaki… - Journal of controlled …, 2019 - Elsevier
… ], and contributes to endocytosis by inducing actin polymerization … caused by cationic cell
penetrating peptides. Moreover, it has been … against these intracellular signaling in the future. …

Cell-penetrating peptides derived from animal venoms and toxins

G Rádis-Baptista - Toxins, 2021 - mdpi.com
… membranes of cells and intracellularly transport diverse types … covalently conjugated with
platinum and gold nanoparticles … -independent endocytosis to exert their effect on intracellular

Cell-penetrating peptides: Promising therapeutics and drug-delivery systems for neurodegenerative diseases

M Pirhaghi, F Mamashli… - Molecular …, 2024 - ACS Publications
endocytosis, also known as receptor mediated endocytosis, … integrity of the cell and control
molecular trafficking, prevent the … ) (PLGA)-based nanoparticle conjugated with a CPP (cyclic …

Advancement and application of novel cell-penetrating peptide in cancer management

S Yadav, P Singh - 3 Biotech, 2023 - Springer
… in CPPs and nanoparticles based on the anticancer drug delivery … , endocytosis which is
based on Clathrin or caveolin … In the case of the conjugate in vivo, which accumulates primarily …

Recent Uses of Lipid Nanoparticles, Cell-Penetrating and Bioactive Peptides for the Development of Brain-Targeted Nanomedicines against Neurodegenerative …

Y Wu, A Angelova - Nanomaterials, 2023 - mdpi.com
… utilizing lipid nanoparticles and cell-penetrating peptides, … that TAT-conjugated nanoparticles
can effectively overcome the … Over ten years, receptor-mediated endocytosis was believed …