Gap junctional intercellular communication as a method to detect and predict carcinogenicity

V Krutovskikh, H Yamasaki - Carcinogenicity, 2021 - taylorfrancis.com
Endogenous and exogenous modulation of gap junctional intercellular communication:
toxicological and pharmacological implications. Life Sci 1993; 53:1-19. Wade MH, Trosko JE, …

Application of cell-cell communication assays to problems of developmental toxicology

R Loch-Caruso - In Vitro Methods in Developmental Toxicology, 2019 - taylorfrancis.com
… that gap junctions may mediate the transfer of an endogenous … of junctional communication
by exogenous substances, … are known to increase gap junctional communication, size, …

Connexin and gap junctions: perspectives from biology to nanotechnology based therapeutics

S Jindal, S Chockalingam, SS Ghosh… - Translational …, 2021 - Elsevier
… The concept of gap junctions and their role in intercellular communication has been known
… biology of connexins in mediating gap junction intercellular communication (GJIC) and their …

A role of connexin 43 on the drug-induced liver, kidney, and gastrointestinal tract toxicity with associated signaling pathways

R Katturajan, SE Prince - Life sciences, 2021 - Elsevier
… through gap junction intercellular communication, regulating … , by excusing endogenous
and exogenous wastes from our … through modulation of intercellular gap junction with targeting …

[HTML][HTML] Brain Disorders and Chemical Pollutants: A Gap Junction Link?

M Mesnil, N Defamie, C Naus, D Sarrouilhe - Biomolecules, 2020 - mdpi.com
… While Cx43 is a negative modulator of neuronal … is now largely banned due to its toxicity.
In the environment, lindane … activated by both endogenous and exogenous ligands including …

[PDF][PDF] … Evaluation Of The Effect Of The Natural Product Compound Chaetoglobosin K On Organochlorine-induced Inhibition Of Astroglial Intercellular Communication.

T Sidorova - 2019 - mercer.openrepository.com
… protective effect of ChK on gap junctions in organochlorine-treated … ChK modulate gap
junctional intercellular communication. ix … physiological or toxicological cues. Certain pesticides …

[HTML][HTML] Cancer prevention and therapy of two types of gap junctional intercellular communication–deficient “cancer stem cell”

JE Trosko - Cancers, 2019 - mdpi.com
… a lack of gap junctional intercellular communication (GJIC). … oncogenes, which block gap
junction function, provide insights … , both endogenous and exogenous chemicals can modulate

[HTML][HTML] Gap junctions and connexins in microglia-related oxidative stress and neuroinflammation: perspectives for drug discovery

G Caruso, L Di Pietro, F Caraci - Biomolecules, 2023 - mdpi.com
… We will then discuss how pharmacological modulation of … N-acetylcysteine, can modulate
the activity of connexins and … given by exogenous (eg, bacterial infection) or endogenous (eg…

[HTML][HTML] Gap junction-dependent and-independent functions of Connexin43 in biology

Y Zhu - Biology, 2022 - mdpi.com
… [15], and gap junction-modulating molecules as potential … It is worth noting that the identity
of the endogenous Cx43 … Where does this toxicity come from? This question may even …

[HTML][HTML] Role and posttranslational regulation of Cx46 hemichannels and gap junction channels in the eye lens

MA Retamal, GA Altenberg - Frontiers in Physiology, 2022 - frontiersin.org
… form hemichannels and gap junction channels that … gap junction channels in the lens under
physiological conditions and in the formation of cataracts, with emphasis on the modulation