Calcium Regulation of Connexin Hemichannels

E Bayraktar, D Lopez-Pigozzi, M Bortolozzi - International Journal of …, 2024 - mdpi.com
… are of paramount importance for intercellular communication. In … While [Ca2+]e acts as a
spatial modulator of the HC opening, … the exogenous mCx45 and the endogenous hCx45 [96]. …

Pesticides and their impairing effects on epithelial barrier integrity, dysbiosis, disruption of the AhR signaling pathway and development of immune-mediated …

C Lima, MAP Falcão, JGS Rosa, GR Disner… - International Journal of …, 2022 - mdpi.com
… to cause substantial long-lasting toxicity that—combined with … has been shown to modulate
epithelial barrier permeability, … as a detector of endogenous and exogenous factors. AhR …

On the potential origin and characteristics of cancer stem cells

JE Trosko - Carcinogenesis, 2021 - academic.oup.com
… (such as inflammation, cell toxicity, cell proliferation, inhibition … modulation of the different
forms of cell-cell communication in … These cells had both the endogenous and exogenous Oct4 …

Gap junctions and breast cancer dormancy

G Sinha, AI Ferrer, CA Moore, Y Naaldijk… - Trends in cancer, 2020 - cell.com
… The pathways that keep CSCs dormant are complex and include indirect and direct intercellular
communication, which allows cells to survive immune evasion partly through increased …

IL-10 enhances cell-to-cell communication in chondrocytes via STAT3 signaling pathway

D Guo, S Kan, L Zhang, Z Niu, M Duan, Y Liu, X Pu… - Cellular …, 2023 - Elsevier
… -10-modulated cell-to-cell communication in chondrocytes and … Exogenous addition or
endogenous overexpression of IL-10 … could enhance gap junction intercellular communication in …

Exosomal delivery of therapeutic modulators through the blood–brain barrier; promise and pitfalls

M Heidarzadeh, Y Gürsoy-Özdemir, M Kaya… - Cell & Bioscience, 2021 - Springer
… role in cellular homeostasis, intracellular communication, and … , it has been shown that
endogenous brain exosomes are … existence of both endogenous and exogenous exosomes within …

Endogenous and exogenous regulation of redox homeostasis in retinal pigment epithelium cells: An updated antioxidant perspective

Y Markitantova, V Simirskii - International Journal of Molecular Sciences, 2023 - mdpi.com
… Disturbed iron metabolism and toxicity due to accumulation in the cell is an important … of
the exogenous precursor of melatonin (N-acetyl-5-methoxytryptamine) in the modulation of the …

Applicability of scrape loading-dye transfer assay for non-genotoxic carcinogen testing

I Sovadinová, BL Upham, JE Trosko… - International Journal of …, 2021 - mdpi.com
… chemicals on GJIC in toxicological and tumor promotion research. In … Here, typically, (1)
exogenous and endogenous tumor … was elicited by immediate modulations of signal transduction …

The concept of “cancer stem cells” in the context of classic carcinogenesis hypotheses and experimental findings

JE Trosko - Life, 2021 - mdpi.com
… that can inhibit gap junction intercellular communication, such as … can modulate gap
junctional intercellular communication is … by endogenous or exogenous epigenetic chemicals. …

Tea and its phytochemicals: Hidden health benefits & modulation of signaling cascade by phytochemicals

S Bag, A Mondal, A Majumder, A Banik - Food Chemistry, 2022 - Elsevier
… EGCG inhibits gap junctional intercellular communication in … connection among exogenous
and endogenous antioxidants which … works against this type of toxicity. The CCL4 treated rat …