Endothelial to mesenchymal transition: role in physiology and in the pathogenesis of human diseases
S Piera-Velazquez, SA Jimenez - Physiological reviews, 2019 - journals.physiology.org
… to undergo endothelial to mesenchymal transition (EndMT), a … EndMT is a complex biological
process in which endothelial … be involved in the pathogenesis of various fibrotic disorders. …
process in which endothelial … be involved in the pathogenesis of various fibrotic disorders. …
Endothelial-to-mesenchymal transition: Pathogenesis and therapeutic targets for chronic pulmonary and vascular diseases
X Lu, J Gong, PA Dennery, H Yao - Biochemical pharmacology, 2019 - Elsevier
… Both pulmonary hypertension and lung fibrosis occur in long-term survivors with … We
then focus on the role of EndoMT in the pathogenesis of these chronic lung diseases, …
then focus on the role of EndoMT in the pathogenesis of these chronic lung diseases, …
[HTML][HTML] The contribution of mesenchymal transitions to the pathogenesis of systemic sclerosis
… (19, 26, 27), indicating that this process is shared by many fibrotic disorders. Pericytes were
… that may regulate the endothelial-to-mesenchymal transition (EndoMT) process in systemic …
… that may regulate the endothelial-to-mesenchymal transition (EndoMT) process in systemic …
The Role of Endothelial-to-Mesenchymal Transition (EndoMT) in Organ Fibrosis
JG Xie, DP Wang - American Journal of Medical and Clinical Research & …, 2023 - ajmcrr.com
… myofibroblasts (EndoMT) during the development of organ fibrosis. In this review, we discuss
the role of EndoMT in renal fibrosis, cardiac fibrosis and pulmonary fibrosis and summarize …
the role of EndoMT in renal fibrosis, cardiac fibrosis and pulmonary fibrosis and summarize …
[HTML][HTML] Emerging roles of inflammation-mediated endothelial–mesenchymal transition in health and disease
Y Yoshimatsu, T Watabe - Inflammation and Regeneration, 2022 - Springer
… the pathogenesis of certain hereditary human vascular diseases… as an endothelial–mesenchymal
transition (EndoMT) inducer… and a novel biomarker for EndoMT in human liver fibrosis. …
transition (EndoMT) inducer… and a novel biomarker for EndoMT in human liver fibrosis. …
[HTML][HTML] The role of endothelial-to-mesenchymal transition in cardiovascular disease
… EndoMT and EndoMT-mediated pathogenesis. Most investigations have been limited to
exploring endothelial and mesenchymal … switch in cardiac fibrosis and other fibrotic diseases [31]…
exploring endothelial and mesenchymal … switch in cardiac fibrosis and other fibrotic diseases [31]…
Endothelial-to-mesenchymal transition in systemic sclerosis
P Di Benedetto, P Ruscitti, O Berardicurti… - Clinical & …, 2021 - academic.oup.com
… fibrosis and collagen deposition. This process is identified as endothelial-to-mesenchymal
transition (EndMT), … is pivotal to identify early pathogenetic events and new therapeutic targets …
transition (EndMT), … is pivotal to identify early pathogenetic events and new therapeutic targets …
[HTML][HTML] TGF-β-induced endothelial to mesenchymal transition in disease and tissue engineering
J Ma, G Sanchez-Duffhues, MJ Goumans… - Frontiers in cell and …, 2020 - frontiersin.org
… Furthermore, we discuss the role of EndMT in cardiovascular diseases, fibrosis, and cancer,
… for the treatment of diseases associated with/caused by EndMT. But, the discovery of …
… for the treatment of diseases associated with/caused by EndMT. But, the discovery of …
[HTML][HTML] The therapeutic potential of targeting the endothelial-to-mesenchymal transition
… EndMT may prove to be effective as a therapeutic treatment. … how EndMT has been targeted
in different disease contexts. … ) was shown to block EndMT and reduce renal fibrosis [102]. …
in different disease contexts. … ) was shown to block EndMT and reduce renal fibrosis [102]. …
Endothelial to mesenchymal transition (EndMT) and vascular remodeling in pulmonary hypertension and idiopathic pulmonary fibrosis
… transition (EMT) [Citation64]. Indeed, accruing research on EndMT showed that endothelial
… contributes to the pathogenesis of several diseases such as fibrosis, pulmonary arterial …
… contributes to the pathogenesis of several diseases such as fibrosis, pulmonary arterial …