… lung epithelial cells reduces toxicities from exposure to benzo [a] pyrene and cigarette smoke condensate via an aryl hydrocarbon receptor-dependent mechanism
J Chen, P Yakkundi, WK Chan - Toxicological Sciences, 2019 - academic.oup.com
… agents from our environment and diet can be mediated … This receptor is a ligand-activated
transcription factor which … may respond differently than in lung endothelial cells and fibroblasts. …
transcription factor which … may respond differently than in lung endothelial cells and fibroblasts. …
[HTML][HTML] Photopic light-mediated down-regulation of local α1A-adrenergic signaling protects blood-retina barrier in experimental autoimmune uveoretinitis
A Stofkova, D Kamimura, T Ohki, M Ota, Y Arima… - Scientific reports, 2019 - nature.com
… mechanism (ie the inflammation amplifier) in endothelial cells … hypothesized that a similar
mechanism is critical for breaching … ligand-dependent adrenoceptor (AR) down-regulation and …
mechanism is critical for breaching … ligand-dependent adrenoceptor (AR) down-regulation and …
LncRNA-ZFAS1 promotes myocardial ischemia-reperfusion injury through DNA methylation-mediated Notch1 down-regulation in mice
M Li, L Jiao, Y Shao, H Li, L Sun, Q Yu, M Gong… - Basic to Translational …, 2022 - jacc.org
… ligand on the neighboring cell surface interacts with the Notch … In aging mice, NMN and
melatonin can protect against MIRI … the role and mechanism of ZFAS1 in MIRI regulation, as well …
melatonin can protect against MIRI … the role and mechanism of ZFAS1 in MIRI regulation, as well …
Modulation of eNOS/iNOS by nebivolol protects against cyclosporine A-mediated nephrotoxicity through targeting inflammatory and apoptotic pathways
… A role of the modulation of endothelial and inducible nitric … by the down-regulation of
CsA-induced fas ligand. The effect … mechanisms involved in NEB-induced vital organ protection …
CsA-induced fas ligand. The effect … mechanisms involved in NEB-induced vital organ protection …
Down-regulation of the human major histocompatibility complex class I chain-related gene A (MICA) and its receptor is mediated by microRNA-146b-5p and is a …
A Al-Abdallah, I Jahanbani, H Mehdawi, RH Ali… - Experimental and …, 2020 - Elsevier
… A (MICA) and its receptor the natural killer group 2 member D (NKG2D) are major executers
of the anti-tumor defense. This work aimed to study the expression and regulation of MICA-…
of the anti-tumor defense. This work aimed to study the expression and regulation of MICA-…
Mechanisms underlying the influence of oestrogen on cardiovascular physiology in women
S Novella, D Pérez‐Cremades… - The Journal of …, 2019 - Wiley Online Library
… PGI 2 is released from endothelial cells and binds to specific receptors located in the … mice
via ERα-mediated mechanisms. miR-22 down-regulation increases the expression of its target …
via ERα-mediated mechanisms. miR-22 down-regulation increases the expression of its target …
FTY720 (Fingolimod) ameliorates brain injury through multiple mechanisms and is a strong candidate for stroke treatment
Z Wang, M Kawabori, K Houkin - Current medicinal chemistry, 2020 - ingentaconnect.com
… mechanism is mediated by the transient down-regulation … endothelial cells. These functions
might play important roles in … and functional mechanisms related to the original ligand, S1P, …
might play important roles in … and functional mechanisms related to the original ligand, S1P, …
[HTML][HTML] Amyloid-β precursor protein APP down-regulation alters actin cytoskeleton-interacting proteins in endothelial cells
… stimuli and mediates cellular response in endothelial cells by … The identification of molecular
mechanisms responsible for … efforts to preserve and protect healthy vasculature in patients …
mechanisms responsible for … efforts to preserve and protect healthy vasculature in patients …
Down-regulation of aryl hydrocarbon receptor intensifies carcinogen-induced retinal lesion via SOCS3-STAT3 signaling
CH Tsai, Y Lee, CH Li, YW Cheng, JJ Kang - Cell Biology and Toxicology, 2020 - Springer
… hydrocarbon receptor (AHR) is a ligand-activated receptor … In this study, to elucidate how
AHR mediates inflammation … in RPE cells, which protects RPE cells from severe damage and …
AHR mediates inflammation … in RPE cells, which protects RPE cells from severe damage and …
Down-regulation of miR-155 inhibits inflammatory response in human pulmonary microvascular endothelial cells infected with influenza A virus by targeting …
SM Shen, H Jiang, JN Zhao, Y Shi - Chinese Medical Journal, 2020 - mednexus.org
… role as well as the underlying mechanism of miR-155 in the … -155 could protect mice from
influenza and Staphylococcus … that intersect with influenza-mediated lung inflammation, and …
influenza and Staphylococcus … that intersect with influenza-mediated lung inflammation, and …