… Altogether, we show here that endothelial Notch signaling … manner exploiting regulation of
adhesive mechanisms rather than by … mediated by decreased angiocrine Wnt ligand secretion …

… The in silico analysis results indicated that endothelin receptor … a co-crystallized ligand (PDB
ID: 5X93 ) was downloaded from … 11A and B indicated the obvious down-regulation of ETBR …

… capacity with ligands expressed on brain endothelial cells; N-… is associated with significant
down-regulation of the inflammatory … that the protective mechanism of dual-ligand modified …

… We treated human retinal endothelial cells exposed to high … ligand; Ligand for the T-cell-specific
cell surface receptor ICOS. … Induces endocytosis- mediated down-regulation of PVR from …

… ligands of the G protein-coupled receptor APJ, which presents in vascular endothelial cells
and… -II elevation may cause the down-regulation of apelin and its receptor in the late stages of …

… Intriguingly, we observed down-regulation of VE-cadherin … proregressive cues linked to Wnt
ligands (26), Angiopoietin-2 (… specific gene target(s) mediate the proregressive effects of YK-…

… However, the mechanisms underlying these antifibrotic … Ligand-activated FXR inhibits
NF-kB-mediated hepatic and … Src down-regulation by siRNA resulted in increased levels of total …

… Ligand binding results in EGFR homodimerization or … may have been down-regulation of
PI3K/Akt-mediated proliferation- … (B) The protein levels of cyclin D1 and vascular endothelial …

… miR-217 stimulates a senescent phenotype with SIRT1 down-regulation. In endothelial cells,
… Both IL-6 and CC motif chemokine ligand 2 (CCL2) are up-regulated in aged VSMCs, as is …

… and HMOX1-mediated post-translational mechanisms. This … CYP1A1 and CYP1A2 mediated
by AHR-ligands such as the … in a glass bottle protected from light. The solution was then …