GPCR-ErbB transactivation pathways and clinical implications
S Palanisamy, C Xue, S Ishiyama, SVN Prasad… - Cellular …, 2021 - Elsevier
… of both receptor families, the number of receptor and ligand … lysophosphatidic acid (LPA),
thrombin, and endothelin-1 mediate … An S1P1-specfic agonist was also able to protect against …
thrombin, and endothelin-1 mediate … An S1P1-specfic agonist was also able to protect against …
Oxidative stress and new pathogenetic mechanisms in endothelial dysfunction: potential diagnostic biomarkers and therapeutic targets
MG Scioli, G Storti, F D'Amico… - Journal of Clinical …, 2020 - mdpi.com
… the regulation of endothelial cell survival, protecting the cells … MiRNAs mediate the adaptation
of endothelial cells subjected to … that ROS generated from hyperglycemia promotes ligand-…
of endothelial cells subjected to … that ROS generated from hyperglycemia promotes ligand-…
Non-coding RNA regulation of endothelial and macrophage functions during atherosclerosis
… endothelial lining can be viewed as the first line of defense … 1 (ICAM-1) that mediate leukocyte
recruitment from the blood into … activation of inflammatory ligand serum amyloid antigen 3 (…
recruitment from the blood into … activation of inflammatory ligand serum amyloid antigen 3 (…
Tetrahydroxystilbene glycoside improves endothelial dysfunction and hypertension in obese rats: The role of omentin-1
Q Dong, W Xing, K Li, X Zhou, S Wang… - Biochemical …, 2021 - Elsevier
… PPAR-γ is a ligand activated transcription factor that regulates … mechanism of omentin-1 and
TSG-mediated protection … time that down-regulation omentin-1 induces vascular endothelial …
TSG-mediated protection … time that down-regulation omentin-1 induces vascular endothelial …
[PDF][PDF] MiRNA-130a promotes inflammation to accelerate atherosclerosis via the regulation of proliferator-activated receptor γ (PPARγ) expression
F Liu, Y Liu, Y Du, Y Li - Anatolian Journal of Cardiology, 2021 - jag.journalagent.com
… in the vascular wall cells (endothelial and smooth muscle cells) as well … Our results suggested
that down-regulation of miRNA-130a … In addition, PPARγ ligand or agonist can restrain the …
that down-regulation of miRNA-130a … In addition, PPARγ ligand or agonist can restrain the …
Estrogen-mediated protection against coronary heart disease: The role of the Notch pathway
F Fortini, FV Dalla Sega, C Caliceti, E Lambertini… - The Journal of steroid …, 2019 - Elsevier
… endothelial cells (HUVECs) have shown that Notch1 protects … arrows indicate mechanisms
of E2-mediated regulation of … induce the expression of Notch receptors, Notch ligands [58,59], …
of E2-mediated regulation of … induce the expression of Notch receptors, Notch ligands [58,59], …
Intermittent Hypoxia Up-Regulates CCL2, RETN, and TNFα mRNAs in Adipocytes via Down-regulation of miR-452
T Uchiyama, A Itaya-Hironaka, A Yamauchi… - International Journal of …, 2019 - mdpi.com
… ligand 2 (Ccl2) was increased by IH via down-regulation of … Causal mechanisms mediating
the association between IH … in human umbilical endothelial cells (HUVEC) from infants of …
the association between IH … in human umbilical endothelial cells (HUVEC) from infants of …
[HTML][HTML] Molecular basis of protease‐activated receptor 1 signaling diversity
OW Fox, RJS Preston - Journal of Thrombosis and Haemostasis, 2020 - Elsevier
… ligands, synthetic peptides based on the Arg‐46‐cleaved PAR1 peptides confer APC‐like
cell signaling on endothelial cells and protect against … mediates endothelial barrier protection …
cell signaling on endothelial cells and protect against … mediates endothelial barrier protection …
Nox1 downregulators: a new class of therapeutics
… Similarly, the endothelin receptor antagonist darusentan was … a steroid receptor strictly
requires activation by its ligand (eg … AT 1 receptor antagonist olmesartan, that mediate some of …
requires activation by its ligand (eg … AT 1 receptor antagonist olmesartan, that mediate some of …
In vitro vascular-protective effects of a tilapia by-product oligopeptide on angiotensin II-induced hypertensive endothelial injury in HUVEC by Nrf2/NF-κB pathways
J Chen, F Gong, MF Chen, C Li, P Hong, S Sun… - Marine drugs, 2019 - mdpi.com
… by mediation of Ang II; we go deeper into the potential … down-regulation of the production
of NO and ROS by LSGYGP was involved in the protective process, which could help to protect …
of NO and ROS by LSGYGP was involved in the protective process, which could help to protect …