Galectin-3 protects against ischemic stroke by promoting neuro-angiogenesis via apoptosis inhibition and Akt/Caspase regulation
UV Wesley, IC Sutton, K Cunningham… - Journal of Cerebral …, 2021 - journals.sagepub.com
… showed down regulation of pro-apoptotic and inflammatory genes including Fas-ligand, and
… clotting tendencies as well as endothelial dysfunction. We next investigated the molecular …
… clotting tendencies as well as endothelial dysfunction. We next investigated the molecular …
Mechanisms of action of metformin and its regulatory effect on microRNAs related to angiogenesis
G Wang, F Lin, Q Wan, J Wu, M Luo - Pharmacological Research, 2021 - Elsevier
… mechanism underlying the metformin-mediated regulation of … of vascular endothelial growth
factor receptors (VEGFR) [16], … angiogenesis via regulating the PTPRD- CXC motif ligand 8 (…
factor receptors (VEGFR) [16], … angiogenesis via regulating the PTPRD- CXC motif ligand 8 (…
Inactivation of endothelial adenosine A2A receptors protects mice from cerebral ischaemia‐induced brain injury
… post-stroke outcomes via down-regulation of inflammation. … other possible mechanisms in
A 2A receptor-mediated, post-… A 2A receptors in brain endothelial cells mediate inflammation …
A 2A receptor-mediated, post-… A 2A receptors in brain endothelial cells mediate inflammation …
[HTML][HTML] SMAD6 transduces endothelial cell flow responses required for blood vessel homeostasis
DL Ruter, Z Liu, KM Ngo, A Marvin, DB Buglak… - Angiogenesis, 2021 - Springer
… -associated genes and down regulation of junction-associated … arterial laminar flow with
protection from atherosclerosis, and … the ligand Dll4 and requires Notch-mediated transcription (…
protection from atherosclerosis, and … the ligand Dll4 and requires Notch-mediated transcription (…
Mechanisms of podocyte injury and implications for diabetic nephropathy
F Barutta, S Bellini, G Gruden - Clinical Science, 2022 - portlandpress.com
… Nephrin down-regulation is observed in early human DN and correlates with both albuminuria
… , glomerular endothelial cells (GECs) and mesangial cells release slit guidance ligand 2 (…
… , glomerular endothelial cells (GECs) and mesangial cells release slit guidance ligand 2 (…
HDAC3 inhibition prevents oxygen glucose deprivation/reoxygenation‐induced transendothelial permeability by elevating PPARγ activity in vitro
… junction protein Claudin-5 down-regulation. And these effects … activity is regulated by various
endogenous ligands and post-… protects against OGD/R-induced cerebral endothelial barrier …
endogenous ligands and post-… protects against OGD/R-induced cerebral endothelial barrier …
[HTML][HTML] The role of KLF2 in the regulation of atherosclerosis development and potential use of KLF2-targeted therapy
SA Dabravolski, VN Sukhorukov, VA Kalmykov… - Biomedicines, 2022 - mdpi.com
… role in regulating atheroprotective effects in endothelial cells. We … in activating various defense
mechanisms against OS and … also participates in DF-mediated KLF2 down-regulation [37]. …
mechanisms against OS and … also participates in DF-mediated KLF2 down-regulation [37]. …
[HTML][HTML] Tumor angiogenesis: causes, consequences, challenges and opportunities
R Lugano, M Ramachandran, A Dimberg - Cellular and Molecular Life …, 2020 - Springer
… of cellular and molecular mechanisms involved in tumor … neo-vascularization from endothelial
progenitor cells. The … recurrence after irradiation is mediated by vasculogenesis and not …
progenitor cells. The … recurrence after irradiation is mediated by vasculogenesis and not …
Vitamin E: regulatory role on signal transduction
JM Zingg - IUBMB life, 2019 - Wiley Online Library
… to cultured vascular endothelial cells by down-regulating CD36 … -regulated by its ligand LDL,
the CD36 scavenger receptor is … vitamin E and atorvastatin by down-regulation of CD36, but …
the CD36 scavenger receptor is … vitamin E and atorvastatin by down-regulation of CD36, but …
[HTML][HTML] Impairment of NKG2D-mediated tumor immunity by TGF-β
M Lazarova, A Steinle - Frontiers in immunology, 2019 - frontiersin.org
… the surface of regulatory T cells (Tregs), endothelial cells, platelets… ligand, or without affecting
NK cell viability, indicating that … TGF-β-mediated down-regulation of NKG2D and associated …
NK cell viability, indicating that … TGF-β-mediated down-regulation of NKG2D and associated …