GSH triggered intracellular aggregated-cisplatin-loaded iron oxide nanoparticles for overcoming cisplatin resistance in nasopharyngeal carcinoma
NK Bejjanki, H Xu, M Xie - Journal of Biomaterials …, 2021 - journals.sagepub.com
… to enhance the antitumor activity by reducing the side effects of chemotherapy, minimizing
systemic toxicity, … for NPC patients with primary or secondary chemo-resistance in the future. …
systemic toxicity, … for NPC patients with primary or secondary chemo-resistance in the future. …
Cellular toxicity mechanisms and the role of autophagy in Pt (IV) prodrug-loaded ultrasmall iron oxide nanoparticles used for enhanced drug delivery
L Gutiérrez-Romero, L Rivas-García… - Pharmaceutics, 2021 - mdpi.com
… However, the positive chemotherapeutic effect of cisplatin in most cancers (eg, ovarian, …
iron oxide nanoparticles (<10 nm) loaded with cisplatin (IV) prodrug compared to using cisplatin. …
iron oxide nanoparticles (<10 nm) loaded with cisplatin (IV) prodrug compared to using cisplatin. …
Combination of ovalbumin-coated iron oxide nanoparticles and poly (amidoamine) dendrimer-cisplatin nanocomplex for enhanced anticancer efficacy
… strategy to enhance the anticancer efficacy of cisplatin via a chemotherapeutic agent 4.5…
-inflammation and assisting cisplatin in accelerating tumor toxicity via ROS generation in tumor …
-inflammation and assisting cisplatin in accelerating tumor toxicity via ROS generation in tumor …
[HTML][HTML] Manganese-deposited iron oxide promotes tumor-responsive ferroptosis that synergizes the apoptosis of cisplatin
J Cheng, Y Zhu, X Xing, J Xiao, H Chen, H Zhang… - Theranostics, 2021 - ncbi.nlm.nih.gov
… to generation of reactive oxygen species (ROS) to enhance … lower systemic toxicity compared
to cisplatin. Additionally, Pt-… cells as cisplatin is the first-line chemotherapeutic drug in …
to cisplatin. Additionally, Pt-… cells as cisplatin is the first-line chemotherapeutic drug in …
Doxorubicin/cisplatin-loaded superparamagnetic nanoparticles as a stimuli-responsive co-delivery system for chemo-photothermal therapy
… Superparamagnetic iron oxide nanoparticles were … for enhancing the therapeutic index
while reducing side effects. In … delivery application is its negligible toxicity to normal cells. The …
while reducing side effects. In … delivery application is its negligible toxicity to normal cells. The …
Ultrasmall iron oxide nanoparticles cisplatin (IV) prodrug nanoconjugate: ICP-MS based strategies to evaluate the formation and drug delivery capabilities in single …
D Turiel-Fernández, L Gutiérrez-Romero… - Analytica Chimica …, 2021 - Elsevier
… which may result in an improved and localized drug release mechanism … and less toxic during
circulation than cisplatin providing … of side effects associated to the treatment with cisplatin. …
circulation than cisplatin providing … of side effects associated to the treatment with cisplatin. …
Nanocarriers-mediated drug delivery systems for anticancer agents: an overview and perspectives
… Various novel nanocarrier-mediated drug delivery systems to … , Sorafenib and Cisplatin
chemotherapeutic agents. Citation… imaging of iron oxide nanoparticles based chemotherapy. (A…
chemotherapeutic agents. Citation… imaging of iron oxide nanoparticles based chemotherapy. (A…
TAT peptide-modified cisplatin-loaded iron oxide nanoparticles for reversing cisplatin-resistant nasopharyngeal carcinoma
H Weng, NK Bejjanki, J Zhang, X Miao, Y Zhong… - Biochemical and …, 2019 - Elsevier
… in combining cisplatin with TAT-peptide to enhance cisplatin … curative effects and minimized
side effects by reducing CDDP … the increased intracellular uptake of CDDP, while the toxicity …
side effects by reducing CDDP … the increased intracellular uptake of CDDP, while the toxicity …
Induction of Ferroptosis by an Amalgam of Extracellular Vesicles and Iron Oxide Nanoparticles Overcomes Cisplatin Resistance in Lung Cancer
… Traditional treatments, such as with the chemotherapy drug cisplatin, encounter … Enhanced
Cisplatin Chemotherapy by Iron Oxide Nanocarrier-Mediated Generation of Highly Toxic …
Cisplatin Chemotherapy by Iron Oxide Nanocarrier-Mediated Generation of Highly Toxic …
Construction of redox-responsive tumor targeted cisplatin nano-delivery system for effective cancer chemotherapy
YY Jia, JJ Zhang, YX Zhang, W Wang, C Li… - International Journal of …, 2020 - Elsevier
… multiple advantages over free drugs, including reduced systemic toxicity, improved passive
accumulation in the tumor due to the enhanced permeability and retention (EPR) effects and …
accumulation in the tumor due to the enhanced permeability and retention (EPR) effects and …