EGFR mutation mediates resistance to EGFR tyrosine kinase inhibitors in NSCLC: From molecular mechanisms to clinical research

RF Dong, ML Zhu, MM Liu, YT Xu, LL Yuan… - Pharmacological …, 2021 - Elsevier
Epidermal growth factor receptor (EGFR) is a well-recognized and effective target for NSCLC
therapies, targeted EGFR therapy with EGFR-… EGFR inhibitor that inhibits both EGFR with …

Epidermal growth factor receptor and its role in pancreatic cancer treatment mediated by nanoparticles

CM Grapa, T Mocan, D Gonciar, C Zdrehus… - International journal …, 2019 - Taylor & Francis
… show that overexpressed epidermal growth factor receptor (EGFR) is a … EGFR-targeted
therapy has not shown the results expected, … The ErbB symbol is derivative from the name of the …

Real-world management of patients with epidermal growth factor receptor (EGFR) mutation-positive non–small-cell lung cancer in the USA

Y Li, A Appius, T Pattipaka, A Feyereislova, A Cassidy… - PLoS …, 2019 - journals.plos.org
… of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors as first-line treatment
for EGFR … However, since this variable was derived from administrative or prescription dates, …

[HTML][HTML] Treatment of uncommon EGFR mutations in non-small cell lung cancer: new evidence and treatment

T Zhang, B Wan, Y Zhao, C Li, H Liu, T Lv… - … lung cancer research, 2019 - ncbi.nlm.nih.gov
therapy has led to a new era in the treatment of NSCLC with the development of detection
techniques for epidermal growth factor receptor (EGFR… Nazartinib, a covalent EGFR inhibitor

Dermatologic adverse events associated with selective fibroblast growth factor receptor inhibitors: overview, prevention, and management guidelines

ME Lacouture, V Sibaud, MJ Anadkat… - The …, 2021 - academic.oup.com
… This work reviewed skin AEs reported with FGFR inhibitors … of skin events and provide
effective treatment strategies. Early … /platelet‐derived growth factor receptor multikinase inhibitors, …

Reducing acneiform rash induced by EGFR inhibitors with honeysuckle therapy: A prospective, randomized, controlled study

Z Liu, T Tian, B Wang, D Lu, J Ruan… - Frontiers in …, 2022 - frontiersin.org
Epidermal growth factor receptor (EGFR) targeted therapies, … and panitumumab, and the
EGFR tyrosine kinase inhibitors (TKIs) … Theses EGFR inhibitors (EGFRIs) showed generally low …

Newer-generation EGFR inhibitors in lung cancer: how are they best used?

T Le, DE Gerber - Cancers, 2019 - mdpi.com
epidermal growth factor receptor (EGFR) tyrosine kinase … for EGFR inhibitors and other
molecularly targeted therapies. … on EGFR TKIs in T790M-negative patients was derived from the …

Small molecule inhibitors targeting the EGFR/ErbB family of protein-tyrosine kinases in human cancers

R Roskoski Jr - Pharmacological research, 2019 - Elsevier
… platelet-derived growth factor receptor … The four members of the human epidermal growth
factor receptor gene … EGFR inhibitors that are used in the treatment of NSCLC harboring …

c-Src and EGFR inhibition in molecular cancer therapy: what else can we improve?

S Belli, D Esposito, A Servetto, A Pesapane… - Cancers, 2020 - mdpi.com
… c-Src modulates epidermal growth factor receptor (EGFR) activation and amplifies its
downstream oncogenic signals. In this … receptor (EGFR) [18,19,20], platelet derived growth factor

The new opportunities in medicinal chemistry of fourth-generation EGFR inhibitors to overcome C797S mutation

J He, Z Zhou, X Sun, Z Yang, P Zheng, S Xu… - European Journal of …, 2021 - Elsevier
… Thus, it has become an important target for the treatment of … with NSCLC harbor Epidermal
Growth Factor Receptor (EGFR) … Quinazoline derivatives always were an important nucleus …