… In principle, small molecules are preferred over antibodies … modulation via small molecules
21 ; most small molecules have … Epigenetic modifications include DNA methylation, histone …

… different phenotypes so that epigenetic marks can persist during … of epigenetic marks includes
DNA methylation, histone modification, … Unlike genetic mutations, epigenetic modulation in …

… In addition to the study of germline genetic changes, epigenetic changes affecting the modulation
of … AntimiRNAs are small molecules that bind to the target miRNA and inhibit its activity, …

… Seen the advantages over small molecules… epigenetically reprogrammed and reconstructed
after fertilization [4]. The main mechanisms of epigenetics include DNA methylation, histone …

… study of genome-wide changes in epigenetic mechanisms, including DNA methylation and
… Epigenetics begins with DNA and histone proteins by two mechanisms: methylation of the C5 …

… the inhibitors of DNA methyltransferases or histone deacety… epigenetic modification and the
available epigenetically active drugs. Keywords: Epigenetics, cancer, acetylation, methylation…

… key aberrant epigenetic processes — DNA methylation and … as the effects of epigenetic
modulation on antitumour immune … JMJD3/UTX using the small molecule GSK-J4 led to …

… Both DNA methylation and the modulation of chromatin structure have major effects on the
… acetylation and DNA methylation. Small molecule histone deacetylase (HDAC) and DNA …

… Various mutations in BRPF1 have been implicated in acute leukemias, and therapeutic
targeting of BRPF1 by small molecules is emerging as an attractive strategy for AML therapy [66]. …

… DNA methylation, histone modifications and expression of microRNA (miRNA). This review
mainly summarizes the information of epigenetic … Other small molecules RG108 DNMT1 and …