… The mechanistic contributions of cancer-associated fibroblasts (CAFs) in breast … Epigenetic
switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts…

… In another context, DNMTs may act as regulators for the pro-invasive activity of BCAFs.
Albrengues and colleagues demonstrated that BCAFs pro-invasive activity was sustained by the …

… All together, these studies demonstrated crucial role of DNA methylation activity of the tumor
microenvironment provided sustained head and neck cancer proinvasive activity. Histone …

… one is selecting a promoter to drive the expression of the Cre … The most widely used fibroblast
drivers and their caveats are … improved understanding of the epigenetic regulation of CAF …

… are induced as normal fibroblasts transition into CAFs. Establishing the … epigenetic
modifications and alterations in stromal CAFs and sheds light on the mechanism by which fibroblasts …

… Cancer-associated fibroblasts (CAFs) have previously been … tumor cell invasion: their
pro-invasive secretory profile and ability … evidence that epigenetic regulation via EHMT2 can drive …

… drive tumorigenesis [3]. These genes fall … convert endemic MSCs into cancer-associated
MSCs as well [161]. Tissue MSCs and BM MSCs recruited by the cancer are also epigenetically …

… tumors are the tumor-associated fibroblasts (TAFs) or cancer-associated fibroblasts (CAFs),
a … However, we still lack a complete picture of how miRNAs drive the aberrant activation of …

… Epigenetic regulation has emerged as a new mechanism that underlies the conversion of
fibroblasts into … intercellular physical dynamics that drive collective cancer cell invasion 106 . …

… neoplastic lesions and are known as cancer-associated fibroblasts (CAFs). The … pro-invasive
activation of CAF via DNA methyltransferase DNMT1 and DNMT3b-dependent epigenetic …