Genetics and epigenetics of bone remodeling and metabolic bone diseases

L Oton-Gonzalez, C Mazziotta, MR Iaquinta… - International Journal of …, 2022 - mdpi.com
… process, ultimately leading to a large variety of metabolic bone … and epigenetics of the
bone remodeling process. Moreover, the current findings behind the genetics of metabolic bone

Epigenetic regulation of bone remodeling by natural compounds

N Raut, SM Wicks, TO Lawal, GB Mahady - Pharmacological research, 2019 - Elsevier
… on these specific natural compounds and their epigenetic regulation of bone remodeling. …
of the molecular and epigenetic mechanisms that regulate bone remodeling will significantly …

New insights into the epigenetics of osteoporosis

JG Letarouilly, O Broux, A Clabaut - Genomics, 2019 - Elsevier
… Here, we summarize recent findings on the role of epigenetics in the modulation of mechanisms
… in the bone remodeling process described in human studies that address the epigenetic

The roles of epigenetics regulation in bone metabolism and osteoporosis

F Xu, W Li, X Yang, L Na, L Chen, G Liu - Frontiers in cell and …, 2021 - frontiersin.org
… Studies have shown that epigenetic mechanisms are … , bone remodeling and other bone
metabolism-related processes. Abnormal epigenetic regulation can lead to a series of bone

Bone remodeling: histone modifications as fate determinants of bone cell differentiation

SJ Yi, H Lee, J Lee, K Lee, J Kim, Y Kim… - International journal of …, 2019 - mdpi.com
… derived from mesenchymal stem cells, responsible for bone formation. Osteoclasts are large
… for bone resorption. The lineage-specific differentiation of bone cells requires an epigenetic

Role of epigenetics in alveolar bone resorption and regeneration around periodontal and peri‐implant tissues

F Asa'ad, A Monje, L Larsson - European journal of oral …, 2019 - Wiley Online Library
epigenetic modifications and bone metabolism has been thoroughly investigated in bone
remodeling… the relationship between epigenetic modifications and alveolar bone loss related to …

The mechanism of bone remodeling after bone aging

H Fang, Z Deng, J Liu, S Chen, Z Deng… - Clinical Interventions in …, 2022 - Taylor & Francis
… Citation7 In general, the aging process encompasses genomic damage and telomere
reduction epigenetic changes that alter the protein balance and trigger nutrient perception …

Mechanical regulation of bone remodeling

L Wang, X You, L Zhang, C Zhang, W Zou - Bone research, 2022 - nature.com
Bone remodeling is a lifelong process that gives rise to a mature, dynamic bone structure
via a balance between bone … of bones to dynamic mechanical forces, altering bone mass in …

Role of epigenomics in bone and cartilage disease

JBJ van Meurs, CG Boer… - Journal of Bone and …, 2019 - academic.oup.com
… Although cartilage does not undergo a remodeling process as bone does, epigenetic
mechanisms also contribute to regulation of chondrogenesis and cartilage maintenance. DNA …

Deregulated miRNAs in bone health: Epigenetic roles in osteoporosis

D Bellavia, A De Luca, V Carina, V Costa, L Raimondi… - Bone, 2019 - Elsevier
… through which miRNAs regulate the interaction between the different cell types in the
bone remodeling unit under physiologic conditions or in bone diseases, are still restricted. …