Advances in epigenetics link genetics to the environment and disease

G Cavalli, E Heard - Nature, 2019 - nature.com
… somatic nuclear transfer 25,26 have shown that chromatin and DNA methylation act as
important ‘epigenetic barriers’ (Fig. 1) that prevent changes in gene expression and cell identity. …

Epigenetics in health and disease

L Zhang, Q Lu, C Chang - Epigenetics in allergy and autoimmunity, 2020 - Springer
… These mechanisms are responsible for the initiation and maintenance of epigenetic silencing
and regulation of the gene expression profile and are cornerstones of a series of cellular …

[HTML][HTML] Epigenetics of aging and disease: a brief overview

C Pagiatakis, E Musolino, R Gornati… - Aging clinical and …, 2021 - Springer
… of gene expression responsible for the aging process of different tissues. Therefore, alteration
of the epigenetic … of gene expression, and the multifactorial nature of epigenetic changes …

[HTML][HTML] Genetics and epigenetics in asthma

P Ntontsi, A Photiades, E Zervas, G Xanthou… - International Journal of …, 2021 - mdpi.com
… firstly subjected to epigenetic alterations [38]. … expression are the most common epigenetic
mechanisms identified and have a regulatory role in immune responses and gene expression

Interplay between genetics and epigenetics in osteoarthritis

SJ Rice, F Beier, DA Young, J Loughlin - Nature Reviews …, 2020 - nature.com
… is that many OA genetic risk signals interact with, map to or correlate with epigenetic mediators.
This discovery implies that epigenetic mechanisms, and their effect on gene expression, …

Genetics and epigenetics in obesity

K Rohde, M Keller, L la Cour Poulsen, M Blüher… - Metabolism, 2019 - Elsevier
… However, how eating habits, food preference and physical activity affect gene expression
through epigenetic mechanisms are not known to an extent that it could be used for a …

The impact of epigenetics on cardiovascular disease

D Prasher, SC Greenway… - Biochemistry and Cell …, 2020 - cdnsciencepub.com
… As important epigenetic modulators of gene expression, several lncRNAs have been
shown to play an important regulatory role in diverse cardiovascular pathologies, including the …

Epigenetics and depression

S Penner-Goeke, EB Binder - Dialogues in clinical neuroscience, 2019 - Taylor & Francis
… It has been proposed that epigenetic mechanisms could mediate the … genetic and
environmental factors can be integrated. Epigenetics refers to processes affecting gene expression

Modern epigenetics methods in biological research

Y Li - Methods, 2021 - Elsevier
Epigenetic mechanisms manipulate various physiological and pathological processes
through regulations of relevant gene expressions via changing the accessibility of epigenetic

[HTML][HTML] DNA hypermethylation associated with upregulated gene expression in prostate cancer demonstrates the diversity of epigenetic regulation

I Rauluseviciute, F Drabløs, MB Rye - BMC medical genomics, 2020 - Springer
… not only with downregulation of gene expression, but also that a considerable fraction of
hypermethylated genes is associated with upregulation of gene expression. These two types of …