Epigenetic regulation of B cell fate and function during an immune response
Y Zhang, KL Good‐Jacobson - Immunological Reviews, 2019 - Wiley Online Library
… epigenetic modifications underpinning B cell fate and function during an immune response.
… Furthermore, methylation status of peripheral blood memory B cell subsets separated based …
… Furthermore, methylation status of peripheral blood memory B cell subsets separated based …
Epigenetic programming underpins B cell dysfunction in human SLE
… Peripheral B cells can be divided into subtypes that … epigenetic feature of B cell differentiation
is the targeted and progressive global hypomethylation that occurs as B cells differentiate …
is the targeted and progressive global hypomethylation that occurs as B cells differentiate …
Epigenetic regulation of B cells and its role in autoimmune pathogenesis
… , we discuss epigenetic modifications in different functional B-cell subsets … antibody secretion,
and cytokine production, under different conditions. Maturation and activation of peripheral …
and cytokine production, under different conditions. Maturation and activation of peripheral …
B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids
HN Sanchez, JB Moroney, H Gan, T Shen, JL Im… - Nature …, 2020 - nature.com
… promote thymic production of FOXP3 + Tregs and peripheral … possibly B-cell-intrinsic,
modulation of the antibody response, … IgG3 and IgG2b) antibody response, with a significantly …
modulation of the antibody response, … IgG3 and IgG2b) antibody response, with a significantly …
Regulatory mechanisms of B cell responses and the implication in B cell-related diseases
DY Tsai, KH Hung, CW Chang, KI Lin - Journal of biomedical science, 2019 - Springer
… regulation and epigenetic regulation, on B cell activation, and … Loss of IRF4 leads to impaired
antibody production [27]. XBP-1 … In this study, human peripheral blood B cells were treated …
antibody production [27]. XBP-1 … In this study, human peripheral blood B cells were treated …
New players in the gene regulatory network controlling late B cell differentiation
SN Willis, SL Nutt - Current opinion in immunology, 2019 - Elsevier
… support high rates of antibody production. These processes are … for the development of all
peripheral B-cell subsets including … Epigenetic regulators controlling late B cell differentiation. …
peripheral B-cell subsets including … Epigenetic regulators controlling late B cell differentiation. …
B cell Sirt1 deacetylates histone and non-histone proteins for epigenetic modulation of AID expression and the antibody response
H Gan, T Shen, DP Chupp, JR Taylor, HN Sanchez… - Science …, 2020 - science.org
… proteins (Dnmt1 and NF-κB p65), Sirt1 transduces metabolic cues into epigenetic changes
to play an important B cell–intrinsic role in modulating antibody and autoantibody responses. …
to play an important B cell–intrinsic role in modulating antibody and autoantibody responses. …
Integrative transcriptome and chromatin landscape analysis reveals distinct epigenetic regulations in human memory B cells
… B cell maturation in the bone marrow, peripheral … MBCs are central to the adaptive immune
response, establishing … with different stages of B cell development 38 , no comprehensive …
response, establishing … with different stages of B cell development 38 , no comprehensive …
From loops to looks: transcription factors and chromatin organization shaping terminal B cell differentiation
… between transcription factors, epigenetic changes, and … immune response, based on the
production of highly diverse … marrow and migrate to the peripheral lymphoid organs. In the …
production of highly diverse … marrow and migrate to the peripheral lymphoid organs. In the …
Epigenetic gene regulation in plasma cells
DG Patterson, AK Kania, Z Zuo… - Immunological …, 2021 - Wiley Online Library
… the necessary functions to support antibody production. We also discuss … B cell differentiation
to ASC requires epigenetic … Inhibition of proliferation after stimulation of peripheral blood …
to ASC requires epigenetic … Inhibition of proliferation after stimulation of peripheral blood …