[HTML][HTML] Influenza A virus antibodies with antibody-dependent cellular cytotoxicity function

R Gao, Z Sheng, CC Sreenivasan, D Wang, F Li - Viruses, 2020 - mdpi.com
… ), and antibody-dependent cell-mediated phagocytosis (ADCP)… that these antibodies can
play a critical role in tumor clearance … , ADCC epitopes were identified and these epitope-based …

Regulation of antibody-mediated complement-dependent cytotoxicity by modulating the intrinsic affinity and binding valency of IgG for target antigen

B Wang, C Yang, X Jin, Q Du, H Wu, W Dall'Acqua… - MAbs, 2020 - Taylor & Francis
… as antibody-dependent cell-mediated cytotoxicity (ADCC), … targeting distinct epitopes, but
not overlapping epitopes, exhibited … the critical role monovalent target engagement plays in …

[HTML][HTML] Antibody–receptor interactions mediate antibody-dependent cellular cytotoxicity

Y Sun, S Izadi, M Callahan, G Deperalta… - Journal of Biological …, 2021 - ASBMB
… One of the most significant findings is that afucosylated … commensurate increase in
antibody-dependent cellular cytotoxicity. … Regulation of antibody-dependent cellular cytotoxicity by …

[HTML][HTML] Knowns and unknowns of assaying antibody-dependent cell-mediated cytotoxicity against HIV-1

GK Lewis, ME Ackerman, G Scarlatti, C Moog… - Frontiers in …, 2019 - frontiersin.org
… on B-cells plays a key role in the regulation of Ab responses. … milieu of different viral
epitopes addressed across different … of the HIV-specific Abs may play a decisive role in ADCC, …

[HTML][HTML] The role of IgG Fc receptors in antibody-dependent enhancement

S Bournazos, A Gupta, JV Ravetch - Nature Reviews Immunology, 2020 - nature.com
… and function Whereas the Fab domain of an IgG molecule binds to viral epitopes and can …
well as Fc-mediated engagement and tightly regulated activation of specific FcγR pathways. …

[HTML][HTML] Engineering of humanized antibodies against human interleukin 5 receptor alpha subunit that cause potent antibody-dependent cell-mediated cytotoxicity

JE Kim, DH Lee, K Jung, EJ Kim, Y Choi… - Frontiers in …, 2021 - frontiersin.org
… innate lymphoid cells (ILC2s) play key roles in the induction of … Among the type 2 cytokines,
IL-5 plays the most crucial role … , binding epitopes of anti–IL-5Rα Abs play a critical role in …

[HTML][HTML] Antibody-dependent cellular phagocytosis in antiviral immune responses

MZ Tay, K Wiehe, J Pollara - Frontiers in immunology, 2019 - frontiersin.org
… Other functions, including antibody-dependent cell-mediated … transduction is further regulated
by specific characteristics of … virus, antibody epitope specificity can play an essential role in …

[HTML][HTML] Considerations of antibody geometric constraints on NK cell antibody dependent cellular cytotoxicity

CD Murin - Frontiers in Immunology, 2020 - frontiersin.org
epitope all play roles in the process of antibody dependent … ), a greater understanding of NK
cell mediated ADCC will guide … may play a subtle but significant role in Fc-mediated effector …

[HTML][HTML] Antibody-dependent enhancement:″Evil ″antibodies favorable for viral infections

X Yang, X Zhang, X Zhao, M Yuan, K Zhang, J Dai… - Viruses, 2022 - mdpi.com
… Vaccines and antibody drugs play essential roles in the control … NAbs mediate antibody-dependent
cell-mediated cytotoxicity … of subunit vaccines, selected epitopes on DIII of the ZIKV E …

A review: Antibody-dependent enhancement in COVID-19: The not so friendly side of antibodies

GA Sánchez-Zuno, MG Matuz-Flores… - International journal …, 2021 - journals.sagepub.com
… be elicited against conserved S-epitopes. Despite the above, the … -2 are accessible and play
an essential role in the entry of … However, in some cases, the presence of specific antibodies …