Genetic, environmental and lifestyle determinants of accelerated telomere attrition as contributors to risk and severity of multiple sclerosis

M Hecker, J Bühring, B Fitzner, PS Rommer, UK Zettl - Biomolecules, 2021 - mdpi.com
… Recent data from the UK Biobank indicated that longer … We elaborate on the link between
TL and vitamin D in … Of the various pathogens studied, infection with EpsteinBarr virus (EBV) …

[PDF][PDF] Biomarkers in Multiple Sclerosis: Analysis of the Present Advantages and Look to the Future

I Valentina - J Psychol Neurosci, 2023 - unisciencepub.com
… the potential to trigger the illness are Epstein Barr Virus (EBV) infection, tobacco use, obesity
since childhood, low vitamin D … for MS is facilitated by the use of so-called biobanks. The …

Increased serological response against human herpesvirus 6A is associated with risk for multiple sclerosis

…, N Brenner, J Butt, A Michel, D Jons… - Frontiers in …, 2019 - frontiersin.org
… IE1A and Epstein-Barr virus (EBV) antibody responses for … Swedish microbiological
biobanks potential study participants … blood samples have been identified in Swedish biobanks. …

[图书][B] Exploring the Effect of Genetic, Environmental and Lifestyle Factors on Multiple Sclerosis Susceptibility

O Deeb, S Salameh, A Atallah - 2022 - intechopen.com
… , certain infections such as EpsteinBarr virus (EBV) infection… *15:01, identified vitamin D
as the first example of a gene–… Any of the potential mechanisms may enhance the activation …

An autoantibody signature predictive for multiple sclerosis

CR Zamecnik, GM Sowa, A Abdelhak, R Dandekar… - Nature Medicine, 2024 - nature.com
… human pathogens, including EpsteinBarr virus (EBV) (both … This study presents some
of the first prospective autoantigen-… participants enrolled in a biobanking study, ‘Immunological …

Environmental risk factors in multiple sclerosis: Bridging Mendelian randomization and observational studies

M Vandebergh, N Degryse, B Dubois, A Goris - Journal of Neurology, 2022 - Springer
… obesity, vitamin D deficiency, Epstein-Barr virus infection and … Nested case–control studies
from large biobanks estimated … RCTs investigating the prophylactic potential of vitamin D on …

[HTML][HTML] Mendelian randomization analysis suggests no associations of herpes simplex virus infections with multiple sclerosis

W Zhang, P Wu, R Yin, M Sun, R Zhang… - Frontiers in …, 2022 - frontiersin.org
… We performed a two-sample Mendelian randomization (MR) … trials and genetic-epidemiological
biobanks are still warranted to … that could be construed as a potential conflict of interest. …

[HTML][HTML] Prevention of MS requires intervention on the causes of the disease: Reconciling genes, epigenetics, and Epstein Barr virus

PKA Kearns - Frontiers in Neurology, 2022 - frontiersin.org
… , adolescent obesity and vitamin D deficiency) associations … but not causing variation (for
example, because they are ubiquitous)… Pharmacological targeting of viral enzymes is a potential

Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM

…, RC Brewer, PP Ho, JS Moon, KM Jude, D Fernandez… - Nature, 2022 - nature.com
EpsteinBarr virus (EBV) infection has been epidemiologically … between virus and self-antigens
is a potential mechanism … We then tested plasma samples from patients with MS (n = 36) …

Leptin levels are associated with multiple sclerosis risk

…, L Alonso-Magdalena, D Jons… - Multiple Sclerosis …, 2021 - journals.sagepub.com
… In this nested case–control study using blood samples from Swedish biobanks, we … of
samples, such as a nested case–control study on vitamin D and EpsteinBarr virus serology. Since …