… , including cancer (… of androgen receptor (AR) and its downstream signaling pathways.
Results of recent advances show that the activation of receptor tyrosine kinase (RTK) signaling, …

… also been found in abiraterone-resistant xenograft models [… have indicated that increased
ErbB2 signaling can contribute … by increasing the expression of several androgen receptor …

… [76] demonstrated that ErbB2 signalling was enhanced and associated with AR re-activation
in abiraterone-resistant CRPC xenograft models. Furthermore, concomitant treatment with …

… or may not continue to express varying levels of the androgen receptor (AR) and/or display
various … in EGFR and ErbB2 are generally not observed, ErbB-mediated signaling may play a …

… or metastatic prostate cancer (PCa) is treated with androgen … and androgen receptor (AR)
signalling inhibitors but patients … of HER2+/ErbB2+ breast cancers 19 ) was ineffective in PCa …

… HER2-dependent signaling may support the development of metastatic castration-resistant
prostate cancer (mCRPC) by activating androgen receptor signaling through ligand-…

… therapies for prostate cancer inhibit the androgen receptor (AR) … We identify ERBB2 as a
point of transcriptional convergence … be phosphorylated by EGFR to activate Ras signaling 42 ). …

… Currently, disorders in androgen receptor (AR)-related signaling are widely … ErbB2 stabilized
AR protein, and the expression of ERBB2 was increased in some abiraterone-resistant PCa …

… HER3 signaling in prostate cancer … prostate cancers develop resistance to antiandrogen
therapy has primarily focused on tumor intrinsic mechanisms involving the androgen receptor. …

… abiraterone-resistant cell lines and examine nuclear and cytoplasmic ErbB3 expression …
what effects they may on response to androgen receptor signalling inhibitors (ARSI). I will also …