… One of the reasons is a change in androgen receptor (AR) signaling, which leads to mCRPC.
Taxanes such as docetaxel are used as standard treatments for mCRPC [9]. However, only …

… Excessive activation of androgen receptors (AR) by androgen … They are known as androgen
receptor signaling inhibitors (… and Erb-B2 receptor tyrosine kinase 2 (ErbB2) pathway also …

… Currently, disorders in androgen receptor (AR)-related signaling are widely … ErbB2 stabilized
AR protein, and the expression of ERBB2 was increased in some abiraterone-resistant PCa …

… prognosis in prostate cancer (PCa). The goal was to characterize androgen receptor gene
(AR… and to further understand the somatic genetic heterogeneity of advanced prostate cancer. …

… nuclear receptors, particularly the androgen receptor. We discuss members of the HER
receptor … cues by estrogen-signaling, targeting of the androgen receptor is also feasible with the …

… In this setting, targeting the androgen receptor (AR) signaling axis, whose activation is …
Abiraterone-resistant xenograft models have increased ErbB2 activity. It has been demonstrated …

… the human epidermal growth factor receptor 2 (HER2, ERBB2). … , gene signatures linked to
AR, ESR1 and ERBB2 signaling … has drawn comparisons with prostate cancer and therein the …

… prostate cancers acquire the capacity for androgen‐independent growth and become
resistant to androgen … strategy is needed for aggressive castration‐resistant prostate cancer. …

… Prostate cancer (CaP) is the second leading cause of cancer-related deaths in Western men.
Because androgens drive CaP by activating the androgen receptor (AR), … with signaling …

… with plasma androgen receptor (AR) copy number (CN). … androgen-signaling-targeted
inhibitors, such as increased AR … EPCAM, EGFR, ERBB2: EPCAM expression is present on the …