Estrogen-mediated mechanisms in hypertension and other cardiovascular diseases
B Visniauskas, I Kilanowski-Doroh, BO Ogola… - Journal of human …, 2023 - nature.com
… of E2 are mediated by nuclear estrogen receptors (ERα and … this receptor provides protection
against ischemia/reperfusion … showing the importance of gender disparities in health and …
against ischemia/reperfusion … showing the importance of gender disparities in health and …
[PDF][PDF] ROLE OF ESTROGEN IN CARDIOPROTECTION
MK Niranjan - ijaur.com
… In females, it is involved in the development of sexual characteristics. It's well known that …
in cardioprotection mediated by oestrogen receptors in order to comprehend the role of …
in cardioprotection mediated by oestrogen receptors in order to comprehend the role of …
[HTML][HTML] The Role of 17β-Estradiol and Estrogen Receptors in Regulation of Ca2+ Channels and Mitochondrial Function in Cardiomyocytes
S Mahmoodzadeh, E Dworatzek - Frontiers in Endocrinology, 2019 - frontiersin.org
… E2 synthesis by aromatase plays a role in the E2-mediated effects on CVDs. … mediated
via estrogen receptor alpha (ERα) and beta (ERβ), which are members of the nuclear receptor …
via estrogen receptor alpha (ERα) and beta (ERβ), which are members of the nuclear receptor …
[HTML][HTML] TrkB-mediated sustained neuroprotection is sex-specific and -dependent in adult mice following neonatal hypoxia ischemia
V Chanana, M Hackett, N Deveci, N Aycan… - … of sex Differences, 2024 - Springer
… difference are poorly understood. Here we test the role of the nerve growth factor receptor
… protection is dependent on the presence of the estrogen receptor alpha receptor (\(\text{ER}\…
… protection is dependent on the presence of the estrogen receptor alpha receptor (\(\text{ER}\…
[HTML][HTML] Sex and gender differences in heart failure
V Regitz-Zagrosek - International journal of heart failure, 2020 - ncbi.nlm.nih.gov
… in ischemia/reperfusion injury, 41) ,42) and injury induced by … More precisely, both estrogen
receptors (ER α and ER ß) are … ER mediated collagen regulation underlies sex differences in …
receptors (ER α and ER ß) are … ER mediated collagen regulation underlies sex differences in …
[HTML][HTML] Revealing the influences of sex hormones and sex differences in atrial fibrillation and vascular cognitive impairment
… a member of the nuclear receptor gene superfamily that mediates androgen signaling in …
uncover how sex differences, hormone levels, and hormone receptor signaling influence the …
uncover how sex differences, hormone levels, and hormone receptor signaling influence the …
The mKATP channels and protein-kinase C are involved in the cardioprotective effects of genistein on estrogen-deficient rat hearts exposed to ischemia/reperfusion …
GA Colareda, MI Ragone, P Bonazzola… - Journal of …, 2020 - journals.lww.com
… of the metabolic pathways activated by estrogenic receptors. Taking this background into …
mediated by estrogenic receptors. This mechanism could also explain sex differences found …
mediated by estrogenic receptors. This mechanism could also explain sex differences found …
Estrogen receptor-β agonists modulate T-lymphocyte activation and ameliorate left ventricular remodeling during chronic heart failure
R Rosenzweig, V Kumar, S Gupta… - Circulation: Heart …, 2022 - Am Heart Assoc
… estradiol (E2) concentrations mediate this protection. E2 exerts its effects either via transcription
factors, such as ERs (estrogen receptors… , and all of these receptors are expressed in the …
factors, such as ERs (estrogen receptors… , and all of these receptors are expressed in the …
[HTML][HTML] Sex/gender-and age-related differences in β-adrenergic receptor signaling in cardiovascular diseases
… , showing how sex/gender differences and aging influence β-… cardioprotection following
ischemia/reperfusion (I/R) injury [45]. … Importantly, such an effect is mediated by the activation of …
ischemia/reperfusion (I/R) injury [45]. … Importantly, such an effect is mediated by the activation of …
[HTML][HTML] Estrogen receptor profiles across tissues from male and female Rattus norvegicus
DD Hutson, R Gurrala, BO Ogola… - … of sex Differences, 2019 - Springer
… role for this enzyme in sexual differentiation of females in comparison with males [17]. … cell
type is likely the most important target for estrogenic actions mediated by GPER [30, 31]. ESR2 …
type is likely the most important target for estrogenic actions mediated by GPER [30, 31]. ESR2 …