The roles of estrogen and estrogen receptors in gastrointestinal disease

C Chen, X Gong, X Yang, X Shang… - Oncology …, 2019 - spandidos-publications.com
bowel disease, irritable bowel syndrome and colon cancer. The aim of this review is to provide
an overview of estrogen and its receptors in GI disease… are esophageal adenocarcinoma (…

Estrogen receptors in colorectal cancer: Facts, novelties and perspectives

I Ditonno, G Losurdo, M Rendina, M Pricci, B Girardi… - Current …, 2021 - mdpi.com
Adenocarcinoma is the … bowel diseases, estrogen has also been investigated as a possible
modifier of gut microbiota. Colitis and CRC were induced in mice with and without intestine-…

Estrogen receptor actions in colitis

EL Garcia-Villatoro, CD Allred - Essays in Biochemistry, 2021 - portlandpress.com
bowel diseases (IBDs) are chronic disorders … of other female hormones in ovariectomized
mice receiving AOM/DSS resulted in increased number of colon polyps and adenocarcinomas

Targeting estrogen receptors in colorectal cancer

JW Maingi, S Tang, S Liu, W Ngenya, E Bao - Molecular Biology Reports, 2020 - Springer
… of polyps and tumor progression to invasive adenocarcinoma [9]. These contradictory …
of estrogen receptors, which implies that ERβ mediates the protective effects of estrogen that …

Implications of estrogen and its receptors in colorectal carcinoma

PK Das, J Saha, S Pillai, AKY Lam, V Gopalan… - Cancer …, 2023 - Wiley Online Library
… In this review, we discuss the roles of estrogen receptors and their multiple molecular targets
in … the recurrence of adenocarcinoma of colon (NCT01402648). Taken together, targeting …

[HTML][HTML] G protein-coupled estrogen receptor in colon function, immune regulation and carcinogenesis

D Jacenik, EJ Beswick, WM Krajewska… - World Journal of …, 2019 - ncbi.nlm.nih.gov
… (CD) and ulcerative colitis (UC), the two most commonly diagnosed types of inflammatory
bowel disease (IBD), are characterized by chronic colon inflammation and are associated with …

Estrogen receptor alpha regulates the Wnt/β-catenin signaling pathway in colon cancer by targeting the NOD-like receptors

S Liu, W Fan, X Gao, K Huang, C Ding, G Ma, L Yan… - Cellular signalling, 2019 - Elsevier
… In this study, we investigated the NLRP3 and ERα expression profiles in colon
adenocarcinoma tissues using COAD as an example (Source: http://medical-genome.kribb.re.kr/GENT/…

[HTML][HTML] Profiling estrogen, progesterone, and androgen receptors in colorectal cancer in relation to gender, menopausal status, clinical stage, and tumour sidedness

B Refaat, A Aslam, S Idris, AH Almalki… - Frontiers in …, 2023 - frontiersin.org
… occurs in the gonads, other peripheral tissues, including colon, express the … estrogen,
17β-estradiol (E2) (11–13). Colonic mucosa could also respond to sex hormones, since estrogen (…

[HTML][HTML] Estrogen and progesterone expression in colorectal carcinoma: A clinicopathological study

AAEG Abd ElLateef, AES Mohamed… - Asian Pacific Journal …, 2020 - ncbi.nlm.nih.gov
Estrogen receptor beta (ERβ) is by far the … However, other studies reported that PR expression
level has a significant difference between normal colon, adenoma and adenocarcinoma, …

A novel role for estrogen-induced signaling in the colorectal cancer gender bias

AA Haziman, S Ravinderan, T Thangavelu… - Irish Journal of Medical …, 2019 - Springer
Estrogen receptor-β has been identified as a tumor … had suppressed colon adenocarcinoma
formation while female … to the occurrence of inflammatory bowel diseases. Several genes …