Estrogen receptors in colorectal cancer: Facts, novelties and perspectives

I Ditonno, G Losurdo, M Rendina, M Pricci, B Girardi… - Current …, 2021 - mdpi.com
Adenocarcinoma is the … bowel diseases, estrogen has also been investigated as a possible
modifier of gut microbiota. Colitis and CRC were induced in mice with and without intestine-…

The roles of estrogen and estrogen receptors in gastrointestinal disease

C Chen, X Gong, X Yang, X Shang… - Oncology …, 2019 - spandidos-publications.com
bowel disease, irritable bowel syndrome and colon cancer. The aim of this review is to provide
an overview of estrogen and its receptors in GI disease… are esophageal adenocarcinoma (…

Targeting estrogen receptors in colorectal cancer

JW Maingi, S Tang, S Liu, W Ngenya, E Bao - Molecular Biology Reports, 2020 - Springer
… of polyps and tumor progression to invasive adenocarcinoma [9]. These contradictory …
of estrogen receptors, which implies that ERβ mediates the protective effects of estrogen that …

[HTML][HTML] G protein-coupled estrogen receptor in colon function, immune regulation and carcinogenesis

D Jacenik, EJ Beswick, WM Krajewska… - World Journal of …, 2019 - ncbi.nlm.nih.gov
… (CD) and ulcerative colitis (UC), the two most commonly diagnosed types of inflammatory
bowel disease (IBD), are characterized by chronic colon inflammation and are associated with …

Implications of estrogen and its receptors in colorectal carcinoma

PK Das, J Saha, S Pillai, AKY Lam, V Gopalan… - Cancer …, 2023 - Wiley Online Library
… In this review, we discuss the roles of estrogen receptors and their multiple molecular targets
in … the recurrence of adenocarcinoma of colon (NCT01402648). Taken together, targeting …

Estrogen receptor alpha regulates the Wnt/β-catenin signaling pathway in colon cancer by targeting the NOD-like receptors

S Liu, W Fan, X Gao, K Huang, C Ding, G Ma, L Yan… - Cellular signalling, 2019 - Elsevier
… In this study, we investigated the NLRP3 and ERα expression profiles in colon
adenocarcinoma tissues using COAD as an example (Source: http://medical-genome.kribb.re.kr/GENT/…

The prognostic and therapeutic role of hormones in colorectal cancer: a review

S Nikolaou, S Qiu, F Fiorentino, S Rasheed… - Molecular biology …, 2019 - Springer
… forms of oestrogen receptors: ERα, ERβ and G-protein coupled oestrogen receptor (GPR30) …
GHSR1 can be a target for novel future treatment for early colorectal adenocarcinoma [59]. …

[HTML][HTML] Estrogen and progesterone expression in colorectal carcinoma: A clinicopathological study

AAEG Abd ElLateef, AES Mohamed… - Asian Pacific Journal …, 2020 - ncbi.nlm.nih.gov
Estrogen receptor beta (ERβ) is by far the … However, other studies reported that PR expression
level has a significant difference between normal colon, adenoma and adenocarcinoma, …

[HTML][HTML] Role of estrogen receptors in health and disease

P Chen, B Li, L Ou-Yang - Frontiers in endocrinology, 2022 - frontiersin.org
bowel syndrome (IBS), inflammatory bowel disease (IBD), and colon cancer (CC) are three
major intestinal disorders… Furthermore, pancreatic ductal adenocarcinoma (PDAC) is the most …

[HTML][HTML] Sexual dimorphism in colon cancer

M Abancens, V Bustos, H Harvey, J McBryan… - Frontiers in …, 2020 - frontiersin.org
… inflammatory bowel disease (96). Disrupted expression of estrogen receptors in the intestinal
… anti-secretory effect in a human colonic adenocarcinoma cell line via inhibition of KCNQ1 …