Sexual dimorphism and the role of estrogen in the immune microenvironment of liver metastases

S Milette, M Hashimoto, S Perrino, S Qi, M Chen… - Nature …, 2019 - nature.com
… In addition, spontaneous metastases of pancreatic ductal adenocarcinoma (PDAC) were …
Tamoxifen inhibits the outgrowth of colon carcinoma LM Selective estrogen receptor

The interplay of sex steroids, the immune response, and the intestinal microbiota

F Pace, PI Watnick - Trends in Microbiology, 2021 - cell.com
… such as the G-protein-coupled estrogen receptor GPER-1 and nuclear estrogen receptors α
diseases, inflammatory bowel disease, colorectal cancer, and the susceptibility to intestinal

Phosphatidylinositol 3‐kinase pathway genomic alterations in 60,991 diverse solid tumors informs targeted therapy opportunities

SZ Millis, DL Jardim, L Albacker, JS Ross, VA Miller… - Cancer, 2019 - Wiley Online Library
… ), estrogen receptor 1 (ESR1), and androgen receptor (AR). … MAPK pathway alterations
included colorectal cancers (odds … cell carcinoma, cervix adenocarcinoma, bladder urothelial (…

Pharmacological activation of ERβ by arctigenin maintains the integrity of intestinal epithelial barrier in inflammatory bowel diseases

Y Tao, M Yue, C Lv, X Yun, S Qiao, Y Fang… - The FASEB …, 2020 - Wiley Online Library
Oestrogen receptor beta (ERbeta) is abundantly expressed in normal colonic mucosa, but
declines in colon adenocarcinoma paralleling the tumour’s dedifferentiation. Eur J Cancer. …

Effects of high-fat diet and intestinal aryl hydrocarbon receptor deletion on colon carcinogenesis

EL Garcia-Villatoro, JAA DeLuca… - American Journal …, 2020 - journals.physiology.org
… NEW & NOTEWORTHY Through the use of an intestinal-specific aryl hydrocarbon receptor
(… in intestinal epithelial cells is required to reduce the formation of premalignant colon cancer

Leptin signaling in obesity and colorectal cancer

CT Socol, A Chira, MA Martinez-Sanchez… - International journal of …, 2022 - mdpi.com
… are adenocarcinomas (malignant neoplasms in the colon … in men, but also women if other
factors linked to CRC risk, such … other hand, the anticancer effect of endogenous estrogens in …

Annotation and cluster analysis of long noncoding RNA linked to male sex and estrogen in cancers

S Liu, W Lai, Y Shi, N Liu, L Ouyang, Z Zhang… - NPJ precision …, 2020 - nature.com
… in lung adenocarcinomas and is upregulated in lung adenocarcinoma, colorectal cancer,
and … with the gene estrogen receptor 1 (ESR1) that encodes estrogen receptor α, luteinizing …

The role of ERα36 in cell type-specific functions of estrogen and cancer development

F Mahboobifard, L Dargahi, M Jorjani… - Pharmacological …, 2021 - Elsevier
… It is also suggested to be an important estrogen receptor … target organs, such as the brain,
bone, kidney, colon, liver, … h) [37] and tamoxifen (5 μM) on adenocarcinoma MCF-7 (1 h) [24]. …

[HTML][HTML] Colorectal cancer: an update on treatment options and future perspectives

RM FLORESCU-ŢENEA, AM KAMAL… - Current health …, 2019 - ncbi.nlm.nih.gov
… the G1 phase [31], can bind estrogen receptors, and can reduce RAS and PI3K protein …
of immunohistochemical staining for colorectal adenocarcinoma with negative expression of …

How dysregulated ion channels and transporters take a hand in esophageal, liver, and colorectal cancer

C Stock - Transportome Malfunction in the Cancer Spectrum: Ion …, 2020 - Springer
… In human samples, DMT1 is overexpressed in the progression of Barrett’s metaplasia to
esophageal adenocarcinoma and in metastatic adenocarcinoma. Its overexpression is …