Whole-genome sequencing as a method of prenatal genetic diagnosis: Ethical issues

FJ González-Melado - Clinical Ethics At the Crossroads of Genetic and …, 2023 - Elsevier
… as the future applications of WGS. Second, we will explore the ethical implications of adopting
WGS … We believe that it is moral to do research in order to find genetic markers that would …

Genome sequencing guide: An introductory toolbox to wholegenome analysis methods

AN Burian, W Zhao, TW Lo… - … and Molecular Biology …, 2021 - Wiley Online Library
study to apply technical and ethical concepts from the text. … the peril associated with genome
sequencing techniques. This … methods, and socio-ethical issues associated with genome

[HTML][HTML] Trust and the ethical challenges in the use of whole genome sequencing for tuberculosis surveillance: a qualitative study of stakeholder perspectives

C Jackson, JL Gardy, HC Shadiloo, DS Silva - BMC Medical Ethics, 2019 - Springer
… in implementing WGS data is critical to minimizing stigma for both individuals and entire
communities, “Okay, so I think the political and social issues are tied into the ethical issues, but I …

[HTML][HTML] The full spectrum of ethical issues in pediatric genome-wide sequencing: a systematic qualitative review

J Eichinger, BS Elger, I Koné, I Filges, D Shaw… - BMC pediatrics, 2021 - Springer
impact on scientific research, clinical practice, and wider society [2,3,4]. The use of genome-…
searched with the search strings “whole genome sequencing” AND ethics as well as “whole

Whole-genome sequencing for TB source investigations: principles of ethical precision public health

A Van Rie, DG De Viedma, C Meehan… - … of Tuberculosis and …, 2021 - ingentaconnect.com
Ethical approval was not required for this study as the study did … We therefore reflected on
the potential ethical issues of real-time … using culture-based WGS or other molecular methods. …

Non-invasive prenatal testing for fetal whole genome sequencing: an interpretive critical review of the ethical, legal, social, and policy implications

H Haidar, R Iskander - Can. J. Bioethics, 2022 - HeinOnline
Methods: This study is a critical interpretive literature review exploring and reporting ethical
legal social and policy implications … For instance, when exploring ethical issues surrounding …

Health technology assessment of whole genome sequencing in the diagnosis of genetic disorders: a scoping review of the literature

MC Nurchis, MT Riccardi, G Damiani - … Assessment in Health Care, 2022 - cambridge.org
clinical utility and cost-effectiveness of genome-wide sequencing as well as informing policy
questions by providing analyses of organizational and ethical considerations… from this study

Privacy and ethical challenges in next-generation sequencing

N Martinez-Martin, D Magnus - Expert review of precision medicine …, 2019 - Taylor & Francis
… of research to clinical application. Whole genome sequence data often moves from clinical to
… of machine learning for genetic sequencing and interpretation also poses ethical concerns, …

'There is a lot of good in knowing, but there is also a lot of downs': public views on ethical considerations in population genomic screening

AK Smit, G Reyes-Marcelino, L Keogh, AE Cust… - … of medical ethics, 2021 - jme.bmj.com
ethical considerations raised by participants in our study relate to the ‘traditional’ clinical
aspects of … ↵This can involve whole genome sequencing, exome sequencing, panel testing or …

[HTML][HTML] Ethical implications of epigenetics in the era of personalized medicine

J Santaló, M Berdasco - Clinical epigenetics, 2022 - Springer
… In this review, we will identify and discuss current ethical, legal and social issues of epigenetics
research in the context of personalized medicine. The review covers ethical aspects such …