DNA methylation: shared and divergent features across eukaryotes

RJ Schmitz, ZA Lewis, MG Goll - Trends in Genetics, 2019 - cell.com
… evidence suggests that the functions of DNA methylation may be more diverse and complex
… understanding of DNA methylation profiles and functions in different eukaryotic lineages. …

Encyclopaedia of eukaryotic DNA methylation: from patterns to mechanisms and functions

P Sarkies - Biochemical Society Transactions, 2022 - portlandpress.com
… patterns of DNA methylation across eukaryotic organisms. I will … characterisation of the
evolution of DNA methylation levels and … Remarkably, rapid evolution of DNA methylation patterns …

Universality of the DNA methylation codes in Eucaryotes

B Aliaga, I Bulla, G Mouahid, D Duval, C Grunau - Scientific reports, 2019 - nature.com
… the analysis of the evolution of DNA methylation. Here, an … to infer evolution of DNA methylation
over the eukaryotic tree … such as support vector machine clustering that can use multiple …

Evolution of DNA methylation across ecdysozoa

J Engelhardt, O Scheer, PF Stadler… - … of molecular evolution, 2022 - Springer
DNA methylation. We are therefore showing a very diverse and independent evolution of DNA
methylation … The DNMT clades thus do not have a common ancestor within the eukaryotes

DNA methylation enables transposable element-driven genome expansion

W Zhou, G Liang, PL Molloy… - Proceedings of the …, 2020 - National Acad Sciences
… in modern species, we can infer the prevalence of CpG DNA methylation in evolutionary
time. … In this paper, we suggest that the increase in eukaryotic genome size is a result of the …

Shaping eukaryotic epigenetic systems by horizontal gene transfer

IR Arkhipova, IA Yushenova, F Rodriguez - BioEssays, 2023 - Wiley Online Library
… The evolutionary history of eukaryotic DNA MTases has … methylation in eukaryotes, where
5mC DNA methylation is … of 4mC prediction accuracy using machine learning approaches ( [ 67…

Origin and evolution of DNA methyltransferases (DNMT) along the tree of life: a multi-genome survey

M Bhattacharyya, S De, S Chakrabarti - BioRxiv, 2020 - biorxiv.org
DNA methylation and DNA methylation–associated proteins not only participate in gene …
The highest levels of DNA methylation among all eukaryotes have been observed in plants, …

Discovering DNA methylation, the history and future of the writing on DNA

JD Tompkins - Journal of the History of Biology, 2022 - Springer
… us that essential sequences are conserved over evolution. However, despite the often-…
order complexity of eukaryotic DNA requires seemingly endless epigenetic devices to package …

[HTML][HTML] Evolutionary persistence of DNA methylation for millions of years after ancient loss of a de novo methyltransferase

S Catania, PA Dumesic, H Pimentel, A Nasif… - Cell, 2020 - cell.com
… One example of this division of labor is found in the mammalian DNA methylation system.
Here, de novo methylation is principally catalyzed by the Dnmt3a/b-Dnmt3L complex ( …

[HTML][HTML] DNA methylation: a historical perspective

AL Mattei, N Bailly, A Meissner - Trends in Genetics, 2022 - cell.com
… rapidly growing number of base-resolution methylation maps. Despite this, several … of DNA
methylation patterns remain under investigation. Here, we review the field of DNA methylation