Evaluating lifespan tissue structure: Comparing CSD signal fraction and VBM grey matter density

JC Blair, BT Newman, TJ Druzgal - Proceedings of the ISMRM …, 2019 - archive.ismrm.org
Constrained spherical deconvolution (CSD), a recently developed diffusion MRI analysis
technique, can be used to obtain whole-brain signal fractions from grey-matter-like, white-
matter-like, and CSF-like tissue. This study evaluates the CSF compartment present in grey
matter (GM-CSF) over the lifespan, and compares it to grey matter density (GMD), obtained
through Voxel Based Morphometry. Results of this study reveal a complimentary relationship
between GM-CSF and GMD across the lifespan, but not amongst a younger cohort. Results …
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