Evaluating Trastuzumab in the treatment of HER2 positive breast cancer

R Jaques, S Xu, A Matsakas - 2020 - digitum.um.es
… receptor and its downstream anomalies will also be discussed, as … The HER2 gene (ErbB2)
is located on chromosome 17q12. … outcomes indicates that evaluation of HERstatus is of vital …

Breast cancer: a molecularly heterogenous disease needing subtype-specific treatments

U Testa, G Castelli, E Pelosi - Medical Sciences, 2020 - mdpi.com
… in the evaluation and treatment of patients with breast cancer, … recurrent abnormalities
occurring in breast cancer have been … in metastatic breast cancers; in fact, 70% of the ERBB2

Phase II study (KAMELEON) of single‐agent T‐DM1 in patients with HER2‐positive advanced urothelial bladder cancer or pancreatic cancer/cholangiocarcinoma

EGE de Vries, J Rüschoff, M Lolkema… - Cancer …, 2023 - Wiley Online Library
… receptor 2 (HER2/ERBB2)–positive breast cancer. We aimed to … However, it has been
proposed that HER2 status should no … and tumor response and to evaluate biomarkers that could …

Molecular alterations in anti-apoptotic BCL2 family proteins in breast cancer cell line models, drug sensitivities and dependencies to guide the development of BCL2 …

IA Voutsadakis - Gene, 2022 - Elsevier
… to evaluate the breast cancer cell lines subset of the CCLE collection for molecular abnormalities
in cell … For example, in clinical HER2 positive breast cancer samples with ERBB2 gene

UroVysionTM Fluorescence In Situ Hybridization in Urological Cancers: A Narrative Review and Future Perspectives

C Ke, Z Hu, C Yang - Cancers, 2022 - mdpi.com
… This review focuses on summarizing the research status of U-… FISH detects chromosomal
or genetic abnormalities in cell … polyploidy on chromosome 3 and chromosome 17. Urinary U-…

[HTML][HTML] Pleomorphic/solid lobular carcinoma of male breast with PALB2 germline mutation: case report and literature review

E Rogges, T Corati, M Amato, D Campagna, J Farro… - Pathologica, 2024 - ncbi.nlm.nih.gov
… the absence of specific syndromic genetic abnormalities such as Klinefelter … genetic risk
assessment based on the personal history of male breast cancer and the recurrence of cancer in …

[HTML][HTML] HER2 amplification by next-generation sequencing in lung carcinoma: a comparison of NGS amplified and non-amplified cases by immunohistochemistry and …

H Kıvrak, H Özakıncı, D Karasoy, SD Sak - Balkan Medical Journal, 2022 - ncbi.nlm.nih.gov
… its evaluation methods are well known in breast carcinoma, … ; also known as EGFR2, ERBB2)
is amplified, resulting in … to re-evaluate the HER2 status of non-small cell lung carcinoma (…

Lobular breast cancer: histomorphology and different concepts of a special spectrum of tumors

M Christgen, G Cserni, G Floris, C Marchio, L Djerroudi… - Cancers, 2021 - mdpi.com
… Furthermore, this review highlights recent advances which have … : (i) assessment of the
E-cadherin IHC status in all BCs considered … However, HER2/ERBB2 mutation is not consistently …

A NARRATIVE REVIEW ON ANALYSIS OF CHROMOSOMAL ANOMALIES FREQUENCY AND VARIETIES IN PHENOTYPICALLY FEMALE PATIENTS …

S Hussain - Student's Journal of Health Research Africa, 2024 - sjhresearchafrica.org
Breast Cancer: Amplification of the HER2 (ERBB2) gene on … outcomes for patients with
HER2-positive breast cancer. … offer insights into the functional status of the endocrine system. …

Comparison of Xpert® Breast cancer STRAT4 assay and immunohistochemistry for the evaluation of breast cancer biomarkers in South African patients

WV Dube - 2020 - scholar.sun.ac.za
ERBB2 and MKI67 in invasive breast carcinoma and compare these results to IHC and FISH
biomarker assessment… In this study ER, PR, HER2 and KI-67 status was evaluated in breast