Paclitaxel's mechanistic and clinical effects on breast cancer
… focused on PTX, its evaluations in preclinical research and … of the HER2 (ERBB2) gene
that encodes a transmembrane … PTX causes cytoskeletal abnormalities in which microtubules …
that encodes a transmembrane … PTX causes cytoskeletal abnormalities in which microtubules …
PI3K inhibitors in breast cancer therapy
H Ellis, CX Ma - Current oncology reports, 2019 - Springer
… In this review, we will discuss the rationale for targeting PI3K/… common signaling abnormalities
observed in breast cancer, … breast cancer, irrespective of PIK3CA mutation status (median …
observed in breast cancer, … breast cancer, irrespective of PIK3CA mutation status (median …
Genetics and Oncology (part 2.). Fundamentals of personalised medicine in the treatment of breast and ovarian cancer
A Doraczyńska-Kowalik… - … Journal of Oncology, 2020 - journals.viamedica.pl
… of receptor tyrosine kinase erbB-2 gene (ERBB2 aka HER2). An … Furthermore, HER2 status
should be re-evaluated in post-… breast cancer, as well as for selected cases of specific-type …
should be re-evaluated in post-… breast cancer, as well as for selected cases of specific-type …
The homologous recombination deficiency scar in advanced cancer: agnostic targeting of damaged DNA repair
V Pacheco-Barcia, A Muñoz, E Castro, AI Ballesteros… - Cancers, 2022 - mdpi.com
… In this review, we aim to summarize the roles of HRD across … trial evaluated PARPi efficacy
in early breast cancer after … excluded chromosome 17 because LOH on chromosome 17 …
in early breast cancer after … excluded chromosome 17 because LOH on chromosome 17 …
Valproic acid and breast cancer: State of the art in 2021
A Wawruszak, M Halasa, E Okon, W Kukula-Koch… - Cancers, 2021 - mdpi.com
… This review focuses on in vitro and in vivo experimental data … status and level of development
of societies, cancer is one of … cancer cells without altering mRNAs levels of EGFR, ErbB2, …
of societies, cancer is one of … cancer cells without altering mRNAs levels of EGFR, ErbB2, …
Potential utility of telomere length assessment in breast cancer in a diagnostic histopathology setting.
… abnormalities that are non-cancerous and occurs more … variables of breast cancer (age,
histological grade, nodal status)… ERBB2 amplification in breast cancer analyzed by fluorescence …
histological grade, nodal status)… ERBB2 amplification in breast cancer analyzed by fluorescence …
DNA methylome in HER2-positive resistant breast cancer
S Palomeras Pairet - 2019 - dugi-doc.udg.edu
… Title: Dual fatty acid synthase and HER2 signaling blockade shows marked antitumor activity
against breast cancer models resistant to Anti-HER2 drugs. Authors: Adriana Blancafort, …
against breast cancer models resistant to Anti-HER2 drugs. Authors: Adriana Blancafort, …
Molecularly targeted therapy towards genetic alterations in advanced bladder cancer
J Thomas, G Sonpavde - Cancers, 2022 - mdpi.com
… This review discusses the key targetable genetic aberrations and summarizes the … of ErbB2
inhibitors. They also noted that when compared to gastric and breast cancer, bladder cancer …
inhibitors. They also noted that when compared to gastric and breast cancer, bladder cancer …
Oncogenic signaling in tumorigenesis and applications of siRNA nanotherapeutics in breast cancer
… In this review, we highlighted the effects of major signaling … ,5-trisphosphate, or the status of
intracellular Ca 2+ storage. It … that is encoded by ERBB2 gene. The transmembrane receptor …
intracellular Ca 2+ storage. It … that is encoded by ERBB2 gene. The transmembrane receptor …
Age-correlated protein and transcript expression in breast cancer and normal breast tissues is dominated by host endocrine effects
T Osako, H Lee, G Turashvili, D Chiu, S McKinney… - Nature Cancer, 2020 - nature.com
… their ER binding site status for the METABRIC expression … ER (ESR1) and HER2 (ERBB2)
subgroups for the METABRIC … this study was an assessment of genetic sources exhibiting age…
subgroups for the METABRIC … this study was an assessment of genetic sources exhibiting age…