… species (ROS), nitric oxide (NO), and reactive nitrogen species (RNS). However, ROS, … , if
compared to previous lines of evidence showing a direct involvement of the nitrergic system in …

… Neurotox Res 4:763–768 Darvesh AS, Yamamoto BK, Gudelsky GA (2005) Evidence for
the involvement of nitric oxide in 3,4-methylenedioxymethamphetamine-induced serotonin …

… In conclusion, the results of the present study provide further evidence that MDMA
administration induces neurotoxic effects in the nigrostriatal system of male and female mice, and …

… of mitochondrial complex I and III, loss in mitochondrial membrane potential (ΔΨm) and
induction of mitochondrial permeability transition. The involvement of mitochondria in the …

… administration may be due to (1) the oxidation of metabolites of MDMA, (2) via the redox
cycling of DA, (3) increased nitric oxide production by nitric oxide synthase, (4) excitotoxicity, and…

… Unfortunately, evidence indicates that MDMA has effects on brain functioning and can
result in increased disease susceptibility. Besides the overproduction of neurotransmitters, …

… IHC staining (serotonin transporter, SERT) showed the evidence of neurotoxicity caused by
MDMA (… should be conducted in the future to provide in-depth evidence for its clinical use. …

… We also investigated the effects of MDMA at normal ambient temperature to provide
further evidence as to the importance of environmental factors on the intensity of MDMA's …

… These results could provide in vivo evidence that describes the concentrations of MDMA
and MDA in plasma, CSF, and brain, as well as their effects on spatial memory and brain …

… has no approved antidote. It is therefore of public health relevance that the current study
provides evidence of a role for 5-… The present study is an import proof of concept foray into the …