Somatostatin, a presynaptic modulator of glutamatergic signal in the central nervous system
A Pittaluga, A Roggeri, G Vallarino… - International Journal of …, 2021 - mdpi.com
… innervating the septum, the striatum, the hippocampus and the … somatostatin immunoreactivity
was high, the sst2 receptors … evidence was published demonstrating that somatostatin …
was high, the sst2 receptors … evidence was published demonstrating that somatostatin …
A role for the neuropeptide somatostatin in the neurobiology of behaviors associated with substances abuse and affective disorders
SL Robinson, TE Thiele - Neuropharmacology, 2020 - Elsevier
… We further summarize evidence of a direct role for the SST … observed in this study was
mediated by an increase in CeA SST … infusion increases striatal dopamine release via presynaptic …
mediated by an increase in CeA SST … infusion increases striatal dopamine release via presynaptic …
Clinical significance of filamin A in patients with acromegaly and its association with somatostatin and dopamine receptor profiles
MCA Coelho, ML Vasquez, LE Wildemberg… - Scientific Reports, 2019 - nature.com
… sst2 expression, sst5 expression, dopamine receptor subtype-2 (D2) expression, somatostatin
receptor … , where it acts as a key mediator of cytoskeleton reorganization 11 . FLNA binds …
receptor … , where it acts as a key mediator of cytoskeleton reorganization 11 . FLNA binds …
Somatostatin and Neurotensin Systems in Schizophrenia
A Induni, F Gil Zbinden, MG López Ordieres - Psychiatry and Neuroscience …, 2021 - Springer
… receptors mediate the inhibition of insulin secretion, and the sst2 receptor seems to mediate
… a culture of dopaminergic neurons, it has been enabled to prove a bidirectional interaction …
… a culture of dopaminergic neurons, it has been enabled to prove a bidirectional interaction …
Somatostatin peptide signaling dampens cortical circuits and promotes exploratory behavior
We sought to characterize the unique role of somatostatin (SST) in the prelimbic (PL) cortex
in mice. We performed slice electrophysiology in pyramidal and GABAergic neurons to …
in mice. We performed slice electrophysiology in pyramidal and GABAergic neurons to …
Structure and Function of Somatostatin and its Receptors in Endocrinology
B Zhang, L Xue, ZB Wu - Endocrine Reviews, 2024 - academic.oup.com
… of currently 8 approved SST2 receptor ligands37. A subsequent … In contrast, cultured striatal
neurons exhibit constitutive D2R-… 13 lower affinities, more evidence is needed to support the …
neurons exhibit constitutive D2R-… 13 lower affinities, more evidence is needed to support the …
Activation of dopamine D2 receptor promotes pepsinogen secretion by suppressing somatostatin release from the mouse gastric mucosa
XY Liu, LF Zheng, YY Fan, QY Shen… - … of Physiology-Cell …, 2022 - journals.physiology.org
… pepsinogen secretion directly through D1-like receptors on chief … D 2 R-mediated suppression
of somatostatin release. … brain striatum medium spiny neurons (81, 82) and the receptors …
of somatostatin release. … brain striatum medium spiny neurons (81, 82) and the receptors …
Molecular and cellular mechanisms underlying somatostatin-based signaling in two model neural networks, the retina and the hippocampus
M Cammalleri, P Bagnoli, A Bigiani - International journal of molecular …, 2019 - mdpi.com
… AMPA and kainate receptors mediate fast synaptic … support the notion that somatostatin, via
the SST 2 receptor, is able to … Definitive evidence for the role of somatostatin in inducing the …
the SST 2 receptor, is able to … Definitive evidence for the role of somatostatin in inducing the …
Excitatory SST neurons in the medial paralemniscal nucleus control repetitive self-grooming and encode reward
J Sun, Y Yuan, X Wu, A Liu, J Wang, S Yang, B Liu… - Neuron, 2022 - cell.com
… Here, we identify that the excitatory somatostatin-positive neurons in the medial … activating
dopamine (DA) neurons in the ventral tegmental area (VTA) and eliciting dopamine release. …
dopamine (DA) neurons in the ventral tegmental area (VTA) and eliciting dopamine release. …
Altered expression of somatostatin signaling molecules and clock genes in the hippocampus of subjects with substance use disorder
… of somatostatin in subjects with substance use disorder and in subjects with major depression.
We also observed increased somatostatin receptor … first evidence for altered somatostatin …
We also observed increased somatostatin receptor … first evidence for altered somatostatin …