The physiological basis of pulmonary arterial hypertension

R Naeije, MJ Richter, LJ Rubin - European Respiratory Journal, 2022 - Eur Respiratory Soc
… The slope of mPAP–cardiac output in pulmonary hypertension on heart failure during exercise
is … As discussed previously [35], this is to be explained by exercise-induced pulmonary

Standardized exercise training is feasible, safe, and effective in pulmonary arterial and chronic thromboembolic pulmonary hypertension: results from a large …

E Grünig, A MacKenzie, AJ Peacock… - European heart …, 2021 - academic.oup.com
exercise training for patients with pulmonary arterial (PAH) and chronic thromboembolic
pulmonary hypertension (CTEPH) has been shown to increase quality of life (QoL), exercise

ERS statement on exercise training and rehabilitation in patients with severe chronic pulmonary hypertension

E Grünig, C Eichstaedt, JA Barberà… - … Respiratory Journal, 2019 - Eur Respiratory Soc
… on patients with pulmonary arterial hypertension (PAH) and … pulmonary arterial pressure
between the groups in this study. … ) and multiprofessional (exercise physiologist and/or physical …

Pulmonary arterial hypertension: diagnosis, treatment, and novel advances

BA Maron, SH Abman, CG Elliott, RP Frantz… - … journal of respiratory …, 2021 - atsjournals.org
… capturing an accurate tricuspid regurgitation jet with echocardiography to estimate PASP
during exercise), focusing on PAP during exercise alone is insufficient for accurately assessing …

Exercise pulmonary hypertension predicts clinical outcomes in patients with dyspnea on effort

JE Ho, EK Zern, ES Lau, L Wooster, CS Bailey… - Journal of the American …, 2020 - jacc.org
… on exercise pulmonary hypertension (9). Here, we sought to investigate the clinical significance
and correlates of exercise pulmonary vascular … of pulmonary arterial hypertension. The …

Screening strategies for pulmonary arterial hypertension

DG Kiely, A Lawrie, M Humbert - European Heart Journal …, 2019 - academic.oup.com
… One genotype–phenotype correlation study has revealed a non-BMPR2 genetic trait associated
with a pulmonary hypertensive response to exercise and hypoxia in relatives of patients …

Management of pulmonary arterial hypertension

JD Mayeux, IZ Pan, J Dechand, JA Jacobs… - Current cardiovascular …, 2021 - Springer
… This review focuses on the therapeutic management and individualized approach to
Group 1 pulmonary arterial hypertension (PAH), utilizing Food and Drug Administration-approved …

… oxygen therapy on exercise capacity and quality of life in patients with pulmonary arterial or chronic thromboembolic pulmonary hypertension: a randomised, placebo …

S Ulrich, S Saxer, ED Hasler, EI Schwarz… - … Respiratory Journal, 2019 - Eur Respiratory Soc
lung disease, the major forms of precapillary pulmonary hypertension (PH) are pulmonary
arterial hypertension … are exertional dyspnoea, impaired exercise performance and reduced …

Pulmonary vascular disease in pulmonary hypertension due to left heart disease: pathophysiologic implications

K Omote, H Sorimachi, M Obokata… - European heart …, 2022 - academic.oup.com
… Because the focus of this analysis is on pulmonary vascular pressure loading downstream
of the RV and PA, rather than left ventricular (LV) responses to exercise, PAWP was defined …

Diagnosis and treatment of pulmonary arterial hypertension: a review

NF Ruopp, BA Cockrill - Jama, 2022 - jamanetwork.com
pulmonary vascular resistance of 3 Wood units or greater. Pulmonary arterial hypertension
… PAH, drug- and toxin-associated PAH, pulmonary veno-occlusive disease, PAH in long-term …