Bacteriophages Combined With Subtherapeutic Doses of Flucloxacillin Act Synergistically Against Staphylococcus aureus Experimental Infective Endocarditis
J Save, YA Que, JM Entenza, C Kolenda… - Journal of the …, 2022 - Am Heart Assoc
… Recently, using a model of experimental infective endocarditis (EE), we observed that
phage therapy alone was as effective as ciprofloxacin alone for the treatment Pseudomonas …
phage therapy alone was as effective as ciprofloxacin alone for the treatment Pseudomonas …
Type IV pili of Streptococcus sanguinis contribute to pathogenesis in experimental infective endocarditis
AM Martini, BS Moricz, LJ Woods… - Microbiology …, 2021 - Am Soc Microbiol
… steps in bacterial endocarditis. We recently used these types of experiments to identify S. …
For these experiments, we compared SK36 as the wild-type parent strain and the isogenic …
For these experiments, we compared SK36 as the wild-type parent strain and the isogenic …
A review of current treatment strategies for infective endocarditis
D Luque Paz, I Lakbar, P Tattevin - Expert Review of Anti-infective …, 2021 - Taylor & Francis
… review to the anti-infective treatment of the main bacteria responsible for infective endocarditis,
ie … Principles of antibacterial treatment for infective endocarditis: from experimental data to …
ie … Principles of antibacterial treatment for infective endocarditis: from experimental data to …
[HTML][HTML] All Staphylococcus aureus bacteraemia-inducing strains can cause infective endocarditis: Results of GWAS and experimental animal studies
S Bastien, S Meyers, W Salgado-Pabón, SG Giulieri… - Journal of Infection, 2023 - Elsevier
… Mice model of infective endocarditis … In a first experiment, we tested whether bacteraemia
and endocarditis strains adhered differently to histamine-inflamed aortic valves. The vegetation …
and endocarditis strains adhered differently to histamine-inflamed aortic valves. The vegetation …
[HTML][HTML] Anti-biofilm approach in infective endocarditis exposes new treatment strategies for improved outcome
CJ Lerche, F Schwartz, M Theut, EL Fosbøl… - Frontiers in Cell and …, 2021 - frontiersin.org
… The history of the experimental model of endocarditis dates to 1878 where Dr. Ottomar
Rosenbach was the pioneer to establish the principal of mechanically induced lesions of the …
Rosenbach was the pioneer to establish the principal of mechanically induced lesions of the …
Antistaphylococcal penicillins vs. cefazolin in the treatment of methicillin-susceptible Staphylococcus aureus infective endocarditis: a quasi-experimental monocentre …
B Lefèvre, B Hoen, F Goehringer, WN Sime… - European Journal of …, 2021 - Springer
… ) infective endocarditis (IE) is still debated in the absence of a randomized controlled trial.
In this quasi-experimental study, … In this quasi-experimental, effectiveness and safety did not …
In this quasi-experimental study, … In this quasi-experimental, effectiveness and safety did not …
[HTML][HTML] Coagulation: At the heart of infective endocarditis
L Liesenborghs, S Meyers, T Vanassche… - Journal of Thrombosis …, 2020 - Elsevier
… A heart valve infection or infective endocarditis is an enigmatic disease that continues to …
If bacteria are injected, these lesions evolve to experimental infective endocarditis lesions …
If bacteria are injected, these lesions evolve to experimental infective endocarditis lesions …
Host-pathogen interactions of clinical S. aureus isolates to induce infective endocarditis
C Schwarz, Y Töre, V Hoesker, S Ameling, K Grün… - Virulence, 2021 - Taylor & Francis
… In preparation for the infection experiments bacteria from overnight culture in Tryptic Soy
Broth (TSB) (shaking conditions, 37 C) were adjusted to OD 578 0.1 in TSB. After 3 h of growth (…
Broth (TSB) (shaking conditions, 37 C) were adjusted to OD 578 0.1 in TSB. After 3 h of growth (…
[HTML][HTML] Isolating crucial steps in induction of infective endocarditis with preclinical modeling of host pathogen interaction
C Schwarz, V Hoerr, Y Töre, V Hösker… - Frontiers in …, 2020 - frontiersin.org
… Aortic valves were removed from each experimental group 24 h post infection and analyzed
by transmission electron microscopy (TEM). In brief, heart valves or catheters were fixed in 2…
by transmission electron microscopy (TEM). In brief, heart valves or catheters were fixed in 2…
[HTML][HTML] … Doses of Vancomycin Synergize with Bacteriophages for Treatment of Experimental Methicillin-Resistant Staphylococcus aureus Infective Endocarditis
J Save, YA Que, J Entenza, G Resch - Viruses, 2022 - mdpi.com
Background. Recurrent therapeutic failures reported for the treatment of methicillin-resistant
Staphylococcus aureus (MRSA) infective endocarditis (IE) with vancomycin may be due to …
Staphylococcus aureus (MRSA) infective endocarditis (IE) with vancomycin may be due to …
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