[HTML][HTML] Aquaporins as prognostic biomarker in prostate cancer

PP Kushwaha, S Verma, S Gupta - Cancers, 2023 - mdpi.com
… patients receive aggressive treatment to avoid potential cancer-… Subcellular localization of
AQP3 in normal human prostate … and AQP7 protein expression in human prostate tissue [98]. A …

Aquaporins 1, 3 and 5 in different tumors, their expression, prognosis value and role as new therapeutic targets

MS Moosavi, Y Elham - Pathology & Oncology Research, 2020 - Springer
… 3–7–9-10 that are nonselective water channels, transferring glycerol and potentially other
… , ZO-1, ZO-2, and claudin-1 affect tumor progression due to their changed localization [41]. …

[HTML][HTML] Aquaglyceroporin-3's expression and cellular localization is differentially modulated by hypoxia in prostate cancer cell lines

A de Almeida, D Parthimos, H Dew, O Smart… - Cells, 2021 - mdpi.com
Aquaporins (AQPs) are cell membrane channels expressed in most tissues, with critical …
appears to be inversely correlated to the metastatic potential of each cell line, with LNCaPs …

[HTML][HTML] Targeting aquaporins in novel therapies for male and female breast and reproductive cancers

S Khan, C Ricciardelli, AJ Yool - Cells, 2021 - mdpi.com
… Increases in aquaporin expression are associated with greater … due to predominant localization
in intracellular organelles [10]. … membranes of human prostate tissue and benign tumors, …

Modulatory effect of aquaporin 5 on estrogen-induced epithelial-mesenchymal transition in prostate epithelial cells

Y Fan, TR Song, Q Wei, L Yang, T Lin… - Chinese Medical …, 2021 - mednexus.org
Human prostate tissues were obtained from the specimen … study found that the human prostate
expressed AQP1, 4, 5, 6… broad potential clinical applications of drugs targeting aquaporins

[HTML][HTML] Aquaporins in cancer biology

CS Moon, D Moon, SK Kang - Frontiers in oncology, 2022 - frontiersin.org
… outline the expression of AQPs in human and rodent models and discuss their potential role
… Cryotherapy is an effective therapy for localized or locally advanced prostate cancer, and a …

Aquaporins in female specific cancers

P Kasa, B Farran, GLV Prasad, GP Nagaraju - Gene, 2019 - Elsevier
… that the expression levels of aquaporins are upregulated in multiple malignancies. The …
The potential success of these approaches will necessitate the elucidation of the roles of …

[PDF][PDF] Targeting Aquaporins in Novel Therapies for Male and Female Breast and Reproductive Cancers. Cells 2021, 10, 215

S Khan, C Ricciardelli, AJ Yool - 2021 - academia.edu
… in plasma membranes of human prostate tissue and benign tumors, was … Expression,
localisation and potential significance of aquaporins in benign and malignant human prostate tissue

[HTML][HTML] Signaling mechanisms and pharmacological modulators governing diverse aquaporin functions in human health and disease

K Wagner, L Unger, MM Salman, P Kitchen… - International Journal of …, 2022 - mdpi.com
… function, scattered AQP4 localization, and reduced AQP4 expression levels compared to
wild-… to a failure of insulin release, potentially significant for diabetes; increased levels of AQP8 …

[HTML][HTML] Combined systematic review and transcriptomic analyses of mammalian aquaporin classes 1 to 10 as biomarkers and prognostic indicators in diverse …

PH Chow, J Bowen, AJ Yool - Cancers, 2020 - mdpi.com
aquaporin expression also have been linked with differences in sensitivity to chemotherapy
treatments, suggesting possible … channels localized in the leading edges of migrating cancer