[HTML][HTML] Prognostic significance of BIRC7/Livin, Bcl-2, p53, Annexin V, PD-L1, DARC, MSH2 and PMS2 in colorectal cancer treated with FOLFOX chemotherapy with …

M Faruk, S Ibrahim, SM Aminu, A Adamu, A Abdullahi… - Plos one, 2021 - journals.plos.org
… CRC can be classified as adenocarcinoma not otherwise … a significant decrease in expression
of Bcl-2 in normal colorectal … The DNA MMR proteins form part of the basis of microsatellite

[HTML][HTML] BCL-XL is crucial for progression through the adenoma-to-carcinoma sequence of colorectal cancer

P Ramesh, TRM Lannagan, R Jackstadt… - Cell Death & …, 2021 - nature.com
… 17 and BCL-2 levels in the TCGA dataset of micro-satellite stable … supported by the decrease
in BCL-2 expression detected upon … , such a decrease in antiapoptotic protein expression is …

[HTML][HTML] Mechanism of apoptosis induced by curcumin in colorectal cancer

NI Ismail, I Othman, F Abas, N H. Lajis… - International journal of …, 2019 - mdpi.com
… In addition, elevated expression of Bcl-2 and deficiency in … colon adenocarcinomas [70].
Curcumin was found to increase Bax expression and decrease Bcl-2 in colon adenocarcinoma

[HTML][HTML] MicroRNAs and apoptosis in colorectal cancer

H Wang - International journal of molecular sciences, 2020 - mdpi.com
BCL-2-interacting mediator of cell death in colon cancer tissues. Abrogation of miR-92a induces
apoptosis in cancer cells, that is, the decrease … cell apoptosis in microsatellite instability (…

[HTML][HTML] Proliferation, apoptosis and their regulatory protein expression in colorectal adenomas and serrated lesions

JC Figueiredo, MN Passarelli, W Wei, DJ Ahnen… - Plos one, 2021 - journals.plos.org
colorectal cancers exhibiting high levels of microsatellite … important in these precursors to
colorectal adenocarcinoma. … a strikingly low expression of pro-apoptotic BCL2 and a low pro- …

[HTML][HTML] Tumor suppressor protein p53 and inhibitor of apoptosis proteins in colorectal cancer—A promising signaling network for therapeutic interventions

Ö Güllülü, S Hehlgans, C Rödel, E Fokas, F Rödel - Cancers, 2021 - mdpi.com
… along with chromosomal (microsatellite) instabilities, high-… Nevertheless, it can inhibit
Bcl-2-associated X protein (Bax) … NAIP and decreases its mRNA and protein expression levels …

Aldolase B impairs DNA mismatch repair and induces apoptosis in colon adenocarcinoma

J Lian, L Xia, Y Chen, J Zheng, K Ma, L Luo… - Pathology-Research and …, 2019 - Elsevier
… with microsatellite instability (MSI) in the TCGA Colon Cancer … the expression of the
apoptosis-related markers Bcl-2, p53, … expression of ALDOB correlated with decreased expression

[HTML][HTML] Microsatellite Status and IκBα Expression Levels Predict Sensitivity to Pharmaceutical Curcumin in Colorectal Cancer Cells

L Lu, R Przybylla, Y Shang, M Dai, M Krohn… - Cancers, 2022 - mdpi.com
… Curcumin enhanced the expression of proapoptotic proteins such as … diminished the
expression of antiapoptotic proteins such as Bcl-2 and Bcl-xL, as well as of cell proliferation proteins

[PDF][PDF] Study of Epstein-Barr virus Infection in Relation to the Immunohistochemical Expression of Bcl-2 gene in Tissues of Patients with Adenocarcinoma of the Colon

SM Zeiny, SHM Ali, JR Zangoor… - Indian Journal of …, 2021 - researchgate.net
expression levels of Bcl-2 and Bax with clinicopathological parameters of colorectal cancers
(27, 28), and found that Bax/Bcl- 2 ratio … to apoptosis, where lower ratio lead to resistance of …

[PDF][PDF] … OF BCL-2 C938A GENE POLYMORPHISM IS PROMISING FOR ASSESSING THE RISK OF OCCURRENCE AND/OR EARLY DIAGNOSIS OF COLORECTAL …

YV Soroka, NP Zykova, OZ Nina, Z Оlha M… - 2022 - embj.org
… men and women diagnosed with colon adenocarcinoma. The homozygous … Bcl-2 ratio was
significantly lower in resected colon tumors compared with sigmoid, rectosigmoid, and rectal