… Prostate cancer (PCa) is the second most common cancer and the fifth leading cause of cancer
mortality in men … that PCa patients treated with combined flutamide and finasteride had a …

… on the results of the placebo-controlled Phase III trials. … The available evidence from the
pivotal placebo-controlled … to metastatic disease and OS in men with nmCRPC. The choice of …

… Prostate cancer (PC) is the second leading cause of cancer-related fatalities among male …
First generation ARAs include drugs such as bicalutamide and flutamide; however, these do …

… However, meta-analyses on various TRT outcomes of placebo-controlled RTCs in men
with … of clinical inconsequential prostate cancer in situ or high-grade prostatic intraepithelial …

… on flutamide-induced androgen deprivation on AR expression was studied in male Wistar
… of interest, as progression from prostatic intraepithelial neoplasia to high grade prostatic …

… -analysis of randomised placebo-controlled trials, investigating the use of testosterone therapy
and its association with prostate cancer, have reported a reduction in prostate cancer risk […

… [ 37 ] PCa begins as prostatic intraepithelial neoplasia and … of nADT with leuprolide and
flutamide reported that the … II, double blind, placebo-controlled randomized trial of degarelix/…

… maximum androgen blockade (with nilutamide, flutamide or cyproterone acetate) vs androgen
… a randomized, placebo-controlled, double-blinded phase 3 trial that allocated 1199 men …

… Some of the earliest drugs to be studied for treatment of PCa were antiandrogens, such
as bicalutamide, flutamide, and nilutamide, nonsteroidal molecules available in oral dosage …

… pro-apoptotic effect on prostate epithelial cells. Multiple studies also … This randomized,
double-blind, placebo-controlled multi-… epithelium, they exhibit weaker efficacy than flutamide and …