[HTML][HTML] Regulatory T cells in peripheral tissue tolerance and diseases
… The loss of function of Foxp3 leads to autoimmune disease in both … Peripheral immune
tolerance is crucial to preventing the … tolerance is a subset of CD4 + Foxp3 + T cells known as …
tolerance is crucial to preventing the … tolerance is a subset of CD4 + Foxp3 + T cells known as …
Regulatory T cells and human disease
S Sakaguchi, N Mikami, JB Wing… - Annual review of …, 2020 - annualreviews.org
… factor FoxP3 in the nucleus and CD25 and CTLA-4 on the cell … autoimmune diseases as
seen with FOXP3 mutations. Fatal … Due to their capacity to induce stable immune tolerance, …
seen with FOXP3 mutations. Fatal … Due to their capacity to induce stable immune tolerance, …
[HTML][HTML] Boosting regulatory T cell function for the treatment of autoimmune diseases–That's only half the battle!
J Schlöder, F Shahneh, FJ Schneider… - Frontiers in …, 2022 - frontiersin.org
… and small intestine which confer immune tolerance to food- and … of activated CD4 + T cells
express low levels of Foxp3 which … as CD3 + CD4 + CD25 high CD127 low Foxp3 + cells (34). …
express low levels of Foxp3 which … as CD3 + CD4 + CD25 high CD127 low Foxp3 + cells (34). …
[HTML][HTML] Treg enhancing therapies to treat autoimmune diseases
PJ Eggenhuizen, BH Ng, JD Ooi - International journal of molecular …, 2020 - mdpi.com
… Regulatory T cells (Tregs) are a small yet critical subset of … to redirect autoimmune responses
to a state of immune tolerance, … as FOXP3+ nTregs, and are enriched for T cell receptors (…
to a state of immune tolerance, … as FOXP3+ nTregs, and are enriched for T cell receptors (…
Treg cells in health and autoimmune diseases: New insights from single cell analysis
C Scheinecker, L Göschl, M Bonelli - Journal of autoimmunity, 2020 - Elsevier
… Defects of regulatory T cells have been described among the … dominant regulator in Treg
cell development and function [[9], [10], [11]]. The role of Foxp3 in regulating immune tolerance …
cell development and function [[9], [10], [11]]. The role of Foxp3 in regulating immune tolerance …
Regulatory immune cells
JB Wing, S Sakaguchi - Clinical Immunology, 2019 - Elsevier
… cell populations, focusing primarily on Foxp3-expressing … regulatory T cells (Tregs) and
other suppressive non–T cells. … not a general finding in autoimmune diseases and may not …
other suppressive non–T cells. … not a general finding in autoimmune diseases and may not …
[HTML][HTML] Regulatory dendritic cells, T cell tolerance, and dendritic cell therapy for immunologic disease
S Ness, S Lin, JR Gordon - Frontiers in Immunology, 2021 - frontiersin.org
… of effector T cells as well as by induction of regulatory T cells (… play more than one role in
immune tolerance. For example, the … of Foxp3 + versus Foxp3 − Treg or, for that matter, CD4 + …
immune tolerance. For example, the … of Foxp3 + versus Foxp3 − Treg or, for that matter, CD4 + …
CD4+CD25-FoxP3+ T cells: a distinct subset or a heterogeneous population?
… and their function in cancer and autoimmune diseases. … , CD4 + CD25 ‒ FoxP3 + cells were
proposed to be a subgroup of Tregs and were reported to be the dominant regulatory T cell (…
proposed to be a subgroup of Tregs and were reported to be the dominant regulatory T cell (…
Regulatory T cells: concept, classification, phenotype, and biological characteristics
Y Du, Q Fang, SG Zheng - … Regulatory cells in human health and diseases, 2021 - Springer
… +Foxp3+ cell population is designated regulatory T cells. … Regulatory T cells regulate peripheral
immune tolerance and … in the development of autoimmune diseases. Functional defects …
immune tolerance and … in the development of autoimmune diseases. Functional defects …
[HTML][HTML] The therapeutic potential of regulatory T cells: challenges and opportunities
F Bayati, M Mohammadi, M Valadi, S Jamshidi… - Frontiers in …, 2021 - frontiersin.org
… 11), immune tolerance, inhibition of autoimmune diseases as well as … FoxP3 − CD4 + T cells
in the periphery and convert to FoxP3 … Treg therapy restores the dominant immune tolerance …
in the periphery and convert to FoxP3 … Treg therapy restores the dominant immune tolerance …