… These precursors arise before E7.5 in mice and start to enter the CNS at E9 through the
blood vasculature before the closure of the blood–brain barrier (BBB). In the CNS, …

… further affect integrity of the blood brain barrier (BBB) and modulate immune … microglia is
considered critical for injury repair and involves clearance of dead cells, whereas bone marrow …

… therapeutic avenues for restoring brain barrier functions. … fluid (CSF) barriers, meninges, and
skull bone marrow. They allow … into the blood or phagocytosed by microglia and astrocytes. …

… for targeting microglia as a potential avenue for mitigating the … cross the blood-brain barrier
(BBB) and contribute to the local … Monocytes originate in the bone marrow from the myeloid …

… specific transporters at the blood-brain barrier (BBB). The latter … Moreover, some studies
reported that bone marrow–derived … demonstrated such effect on microglia after CSF1R deletion …

… represent a new promising avenue for developing myeloid … hematopoetic cells in the bone
marrow with decreased numbers of … –retina barrier between retina and choroid [236]. Further, …

… with the skull and vertebral bone marrow has revealed a new layer … of skull and vertebral
bone marrow anatomy, its contribution of … avenues of cross-talk between the CNS and the bone …

… the blood–brain barrier is compromised, however, an influx of bone marrow-derived cells …
slowly replaced by bone marrow-derived Monocytes. During AD context, not only microglia, but …

… Microglia identity is further complicated: bone marrow-derived blood monocytes that cross
the blood-brain barrier … seminal and opened new avenues for microglia research, their advent …

… microglia, two main types of reactive microglia have been defined: the classically activated
(cytotoxic) (state 2) microglia … intact blood–brain barriers (BBB) and/or CSF–brain barriers, it is …