The exposome and toxicology: a win–win collaboration
R Barouki, K Audouze, C Becker, L Blaha… - Toxicological …, 2022 - academic.oup.com
… to exposome characterization is a needed framework for mechanistic understanding and …
This review considers the consequences of the development of the exposome concept on …
This review considers the consequences of the development of the exposome concept on …
The exposome and health: Where chemistry meets biology
… Large-scale exposome studies provide a systematic … adverse effects on health. If systematic
analysis reveals major … explore the mechanistic role of many other exposome chemicals …
analysis reveals major … explore the mechanistic role of many other exposome chemicals …
[HTML][HTML] Unravelling the chemical exposome in cohort studies: routes explored and steps to become comprehensive
… Most exposome definitions acknowledge that typically only chemicals that enter the … or
organ functions and provoke adverse effects. Hence, the exposome can be described as the …
organ functions and provoke adverse effects. Hence, the exposome can be described as the …
[HTML][HTML] Towards mass spectrometry-based chemical exposome: current approaches, challenges, and future directions
… We review the current chemical exposome measurement … in implementing the concept
of chemical exposome and … the mechanistic basis of the exposome in an affordable way. …
of chemical exposome and … the mechanistic basis of the exposome in an affordable way. …
Defining the scope of exposome studies and research needs from a multidisciplinary perspective
P Zhang, C Carlsten, R Chaleckis… - … science & technology …, 2021 - ACS Publications
… Moreover, experimental and observational studies evaluating adverse effects … for mechanistic
underpinnings for a charged claim related to social inequities driving adverse health effects…
underpinnings for a charged claim related to social inequities driving adverse health effects…
The metabolome: a key measure for exposome research in epidemiology
… adverse effects [7, 8]. Both are enabled by computational power of big data and provide exciting
new opportunities for implementing the exposome into … into the underlying mechanism of …
new opportunities for implementing the exposome into … into the underlying mechanism of …
The Exposome in toxicologic pathology
B Bolon, WM Haschek - Toxicologic Pathology, 2020 - journals.sagepub.com
… teams that assemble data sets for building AOP models, so in this respect toxicologic
pathologists are well positioned to participate in relating mechanistic data to the exposome. …
pathologists are well positioned to participate in relating mechanistic data to the exposome. …
[HTML][HTML] The role of exposomes in the pathophysiology of autoimmune diseases I: toxic chemicals and food
A Vojdani, E Vojdani - Pathophysiology, 2021 - mdpi.com
… -related immune reactions is the oral tolerance mechanism, … in the pathophysiology of
chemical-induced autoimmunity [49,… lectins) that have a detrimental effect on both enterocyte and …
chemical-induced autoimmunity [49,… lectins) that have a detrimental effect on both enterocyte and …
[HTML][HTML] Biomarkers of environmental toxicants: exposure and biological effects
RJ Turesky, K Lu - Toxics, 2020 - mdpi.com
… on mechanistic studies that examine the biological effects of … in implementing the concept
of chemical exposome and … is one of the key events in chemical-induced carcinogenesis. It is …
of chemical exposome and … is one of the key events in chemical-induced carcinogenesis. It is …
The contribution of the exposome to the burden of cardiovascular disease
… are associated with adverse cardiovascular health effects such as … as the driver of the
detrimental effects of the exposome. … , the induced pathological and mechanistic changes in …
detrimental effects of the exposome. … , the induced pathological and mechanistic changes in …