… This analysis identified 28 not repetitive genes with possibly … Functional analysis of genes
with possibly damaging VUS … However, the use of anti-androgen compounds has generated …

… analysis of the anti-androgen resistant cell lines identified … studies have shown that the
androgen receptor (AR) remains … treatment can confer docetaxel cross-resistance 11 , which may …

… These mutations confer ligand promiscuity, but the affinity for … AR L702H single mutation, this
study identifies dexamethasone as … -function analysis of androgen receptor Leu701 mutants …

… F877L mutation has also been shown to confer resistance to … -breaking study, Sadar and
co-workers identified a bisphenol … sponge extract that exhibited anti-androgen activity [109]. The …

… (A) The primary sequence of the androgen receptor contains several functional domains: …
androgen signaling axis to confer resistance, whereas a subset of CRPC will irreversibly lose …

… are the predominant form of anti-androgen therapy given to … (AR) ligand-binding domain
(LBD) point mutations identified … the role of AR gene expression in conferring ARI resistance. …

… frequently identified after treatment resistance emerged. Intriguingly, these hot spot mutations
… and antiandrogens is critical to their function to mutated AR. Actually, since enzalutamide …

… that mutations of AR in PCa under selection by anti-androgen treatment … identified to
be activated, led to gain of function probably due to the selective pressure exerted by anti-androgen …

… Transcriptome analysis identified 1,178 genes up and 648 … variant 7 induce expression of
SRD5A isoforms and confer … cells to anti-androgen treatment by decreasing androgen receptor…

… which function by inhibiting androgen signaling by targeting … by which anti-androgen resistance
occurs have been identified. … responsiveness of androgen receptor mutants obtained by …