Age-related structural and functional changes in the mouse lung

H Schulte, C Mühlfeld, C Brandenberger - Frontiers in physiology, 2019 - frontiersin.org
… To improve our understanding of the structure-function relationships leading to this decline…
lung and their impact on micromechanics and lung function in the aging mouse. Lung function

In-vivo lung fibrosis staging in a bleomycin-mouse model: a new micro-CT guided densitometric approach

L Mecozzi, M Mambrini, F Ruscitti, E Ferrini… - Scientific reports, 2020 - nature.com
… free access to standard rodent chow and softened tap … lung capacity (TLC) or at functional
residual capacity (FRC) 9,40 whereas, to address free breathing variabilities, mice imaged by …

Chemokine receptor 2–targeted molecular imaging in pulmonary fibrosis. A clinical trial

SL Brody, SP Gunsten, HP Luehmann… - American journal of …, 2021 - atsjournals.org
… mixed with rodent chow at 0.5% by weight (24). Mouse … in lungs removed from patients with
pulmonary fibrosis at lung … and three women) with normal lung function (Table E3, human …

Single-cell connectomic analysis of adult mammalian lungs

MSB Raredon, TS Adams, Y Suhail, JC Schupp… - Science …, 2019 - science.org
… As maintaining barrier function is arguably the foremost design criterion in lung tissue … min
for the rodent tissues and 40 min for the large mammals. At this point, the lungs were pushed …

Imaging Cardiovascular and Lung Macrophages With the Positron Emission Tomography Sensor 64Cu-Macrin in Mice, Rabbits, and Pigs

M Nahrendorf, FF Hoyer, AE Meerwaldt… - … Imaging, 2020 - Am Heart Assoc
… We further report that rodent toxicity studies and human radiation dose estimates suggest …
During PET of the thorax, cardiac cine MR images were acquired for cardiac function

Preclinical applications of multi-platform imaging in animal models of cancer

NJ Serkova, K Glunde, CR Haney, M Farhoud… - Cancer research, 2021 - AACR
… B, Physiology-based images in rodent cancer models: (7) high … enhanced microCT of lung
vasculature and small lung tumor using … An anatomic and functional imaging probe for a novel …

Update on the features and measurements of experimental acute lung injury in animals: an official American Thoracic Society workshop report

HS Kulkarni, JS Lee, JA Bastarache… - American journal of …, 2022 - atsjournals.org
… , accurate measure of lung mechanics in small rodents. Third, a … First, impaired lung function,
specifically reduced respiratory … who suggested lung function measurements recommended …

Histopathologic evaluation and scoring of viral lung infection

DK Meyerholz, AP Beck - Mers Coronavirus: Methods and Protocols, 2020 - Springer
… -related variables affecting lung evaluation. When examining rodents versus lungs from
larger … on the size of the lungs, distribution of lung lesions, and overarching goals of the study. …

Identification of lung innervating sensory neurons and their target specificity

Y Su, J Barr, A Jaquish, J Xu… - … of Physiology-Lung …, 2022 - journals.physiology.org
… of lung innervating neurons serves as a foundation for understanding their function in lung.
… Using in situ hybridization combined with retrograde tracing from the lung, we found that lung

In vivo imaging of mitochondrial membrane potential in non-small-cell lung cancer

M Momcilovic, A Jones, ST Bailey, CM Waldmann, R Li… - Nature, 2019 - nature.com
lung cancer, and find distinct functional mitochondrial heterogeneity within subtypes of lung
… F-BnTP has been studied in rodent and canine myocardium to detect myocardial infarction 4…