PFKFB3 in smooth muscle promotes vascular remodeling in pulmonary arterial hypertension
… in lungs of PAH rodents and in platelet-derived growth factor–treated PASMCs. PFKFB3
protein was higher in pulmonary arteries of patients and rodents … right ventricular function. The …
protein was higher in pulmonary arteries of patients and rodents … right ventricular function. The …
[HTML][HTML] CD146-HIF-1α hypoxic reprogramming drives vascular remodeling and pulmonary arterial hypertension
Y Luo, X Teng, L Zhang, J Chen, Z Liu, X Chen… - Nature …, 2019 - nature.com
… cardiac function in two rodent models. This … lungs compared with control lung tissues. To
evaluate whether CD146 expression is associated with disease severity, we studied rodent lung …
evaluate whether CD146 expression is associated with disease severity, we studied rodent lung …
[HTML][HTML] Inhalable dry powder mRNA vaccines based on extracellular vesicles
… ), Lung-Exos exhibited superior distribution to the bronchioles and parenchyma and are
deliverable to the lungs of rodents and … the ability of Lung-Exos to function as an inhalable drug-…
deliverable to the lungs of rodents and … the ability of Lung-Exos to function as an inhalable drug-…
HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction
… Because SAHA has been shown to have a direct beneficial effect on the lungs in rodent
models of induced PH (44), it is possible that the improvements observed in our study are …
models of induced PH (44), it is possible that the improvements observed in our study are …
[HTML][HTML] Pulmonary fibrosis as a result of acute lung inflammation: molecular mechanisms, relevant in vivo models, prognostic and therapeutic approaches
IA Savin, MA Zenkova, AV Sen'kova - International journal of molecular …, 2022 - mdpi.com
… lung disease that steadily leads to lung architecture disruption and respiratory failure. The
development of pulmonary fibrosis is mostly the result of previous acute lung … in the lungs. …
development of pulmonary fibrosis is mostly the result of previous acute lung … in the lungs. …
Air pollution and lung function in children
… We provide a narrative review of air pollution exposures and their associations with child
lung function and lung function growth in general pediatric populations (Box 1). We primarily …
lung function and lung function growth in general pediatric populations (Box 1). We primarily …
[HTML][HTML] Multifunctional angiotensin converting enzyme 2, the SARS-CoV-2 entry receptor, and critical appraisal of its role in acute lung injury
… function of ACE2 as the entry receptor for SARS-CoV-2 has been well established, the
contribution of enzymatic functions of ACE2 to the pathogenesis of COVID-19-related lung injury …
contribution of enzymatic functions of ACE2 to the pathogenesis of COVID-19-related lung injury …
Precision-cut lung slices from bleomycin treated animals as a model for testing potential therapies for idiopathic pulmonary fibrosis
M Cedilak, M Banjanac, D Belamarić… - Pulmonary …, 2019 - Elsevier
… This leads to formation of scar tissue, followed by decline in lung function of the patients.
Aberrant … Administration of bleomycin to rodents induces severe damage of the lung tissue with …
Aberrant … Administration of bleomycin to rodents induces severe damage of the lung tissue with …
[HTML][HTML] The history and mystery of alveolar epithelial type II cells: focus on their physiologic and pathologic role in lung
… on rodents and reported the first successful isolation of a surfactant-producing epithelial cell
from their lungs [2]. … of lung function and allows for the study of regional lung structure [36]. …
from their lungs [2]. … of lung function and allows for the study of regional lung structure [36]. …
Nanoparticle delivery of proangiogenic transcription factors into the neonatal circulation inhibits alveolar simplification caused by hyperoxia
C Bolte, V Ustiyan, X Ren, AW Dunn… - American journal of …, 2020 - atsjournals.org
… ) improves lung structure and function in rodent BPD models, … lung structure and function
after neonatal hyperoxic injury. … nanoparticles on lung structure and function were evaluated …
after neonatal hyperoxic injury. … nanoparticles on lung structure and function were evaluated …