Experimental early‐life febrile seizures cause a sustained increase in excitatory neurotransmission in newborn dentate granule cells
G Hoogland, M Raijmakers, E Clynen… - Brain and …, 2022 - Wiley Online Library
… -associated temporal lobe epilepsy. The dentate gyrus is the … Febrile seizures (FS) are
fever-induced seizures in children till … Since GABA has an initial depolarizing effect on newborn …
fever-induced seizures in children till … Since GABA has an initial depolarizing effect on newborn …
Microglial displacement of GABAergic synapses is a protective event during complex febrile seizures
… Complex febrile seizures (FSs) lead to a high risk of intractable temporal lobe epilepsy …
We investigated morphology change of microglia after inducing simple FSs (5-min FS or one…
We investigated morphology change of microglia after inducing simple FSs (5-min FS or one…
Seizure-induced hilar ectopic granule cells in the adult dentate gyrus
Y Kasahara, H Nakashima, K Nakashima - Frontiers in Neuroscience, 2023 - frontiersin.org
… of seizure-induced ectopic granule cells in the epileptic brain. In … decreased it in a postnatal
febrile seizure (which is thought … Following epileptogenic insults, GABAergic interneurons are …
febrile seizure (which is thought … Following epileptogenic insults, GABAergic interneurons are …
The Role of Hyperexcitable Existing Granule Cells in Seizure-Induced Ectopic Granule Cells
H Tan - MedScien, 2024 - deanfrancispress.com
… Therefore, this paper concentrates on GABA receptors, … of ectopic GCs in the aftermath of
experimental febrile seizures. … between seizures, adult neurogenesis, and their role in epilepsy. …
experimental febrile seizures. … between seizures, adult neurogenesis, and their role in epilepsy. …
The pharmacological assessment of GABAA receptor activation in experimental febrile seizures in mice
… , where immature neurons overwhelm mature neurons. Using experimental approaches
in … GABA A receptor modulators increase epileptic events 10 min after the induction of …
in … GABA A receptor modulators increase epileptic events 10 min after the induction of …
The long-term neurodevelopmental outcomes of febrile seizures and underlying mechanisms
Y Yi, C Zhong, H Wei-Wei - … in Cell and Developmental Biology, 2023 - frontiersin.org
… of FSs with epilepsy in adult, with numbers of … granule cells resulted in granule cell
ectopia that persists into adulthood. FSs induced an upregulation of GABA (A) receptors [GABA …
ectopia that persists into adulthood. FSs induced an upregulation of GABA (A) receptors [GABA …
Febrile Response and Seizures
A Vezzani, T Bartfai - Stress: Physiology, Biochemistry, and Pathology, 2019 - Elsevier
… Although most febrile seizures are benign, prolonged febrile seizures increase the risk of …
by bumetanide after FS rescued the ectopic granule cells as well as development of epilepsy in …
by bumetanide after FS rescued the ectopic granule cells as well as development of epilepsy in …
Under New Management: Transplanted GABAergic Progenitors Control Adult Neurogenesis
GF Buchanan - Epilepsy currents, 2023 - journals.sagepub.com
… These ectopic cells mature into granule cells in the hilus that … mice with Pilocarpine induced
TLE, hilar transplants of GABA … some inciting event (eg, febrile seizure, in utero insult, injury, …
TLE, hilar transplants of GABA … some inciting event (eg, febrile seizure, in utero insult, injury, …
[PDF][PDF] Hippocampal Oxygen Dynamics During and Following Febrile Seizures
S Harris - 2021 - prism.ucalgary.ca
… and adenosine receptors prior to febrile seizure induction. … a brief focal seizure or status
epilepticus in adults. A single … Chapter 1 is a general introduction to epilepsy, febrile seizures…
epilepticus in adults. A single … Chapter 1 is a general introduction to epilepsy, febrile seizures…
Microglia modulate the structure and function of the hippocampus after early-life seizures
… hippocampus such as ectopic granule cells, 12 enhanced … 30 min or 4 h after febrile
seizures, finding that inflammatory … properties after epileptic seizures. Jackson and colleagues …
seizures, finding that inflammatory … properties after epileptic seizures. Jackson and colleagues …