Genetic evidence for an inhibitory role of tomosyn in insulin‐stimulated GLUT4 exocytosis
… We observed that tomosyn bound to GLUT4 exocytic t-SNAREs and arrested the fusion …
SNARE complexes involved in GLUT4 exocytosis. Tomosyn was removed from GLUT4 exocytic t-…
SNARE complexes involved in GLUT4 exocytosis. Tomosyn was removed from GLUT4 exocytic t-…
[PDF][PDF] Inducible Exoc7/Exo70 knockout reveals a critical role of the exocyst in insulin-regulated GLUT4 exocytosis
… We observed that insulin-stimulated GLUT4 exocytosis was … role in insulin-stimulated GLUT4
exocytosis in adipocytes. We … glucose transporter GLUT4 (1–3). Under basal conditions, …
exocytosis in adipocytes. We … glucose transporter GLUT4 (1–3). Under basal conditions, …
Thirty sweet years of GLUT4
… GLUT4 discovery and chronicle additional key findings made in the past 30 years. That
exocytosis of … GLUT4 controls glucose transport into fat and muscle tissues in response to insulin …
exocytosis of … GLUT4 controls glucose transport into fat and muscle tissues in response to insulin …
A detection method for GLUT4 exocytosis based on spontaneous split luciferase complementation
M Endo, M Miyasaki, Q Li, G Kawamura… - Analytical …, 2019 - jstage.jst.go.jp
… of GLUT4, quantitative measurement of GLUT4 exocytosis is indispensable. Herein, we show
a rapid detection system for GLUT4 … Upon insulin-induced GLUT4 exocytosis, GLUT4 was …
a rapid detection system for GLUT4 … Upon insulin-induced GLUT4 exocytosis, GLUT4 was …
Exocytosis proteins: typical and atypical mechanisms of action in skeletal muscle
J Hwang, DC Thurmond - Frontiers in Endocrinology, 2022 - frontiersin.org
… This is particularly relevant to the skeletal muscle field, since STX4 is the sole STX family
member identified in the process of GLUT4 exocytosis. No redundant PM-localized alternate …
member identified in the process of GLUT4 exocytosis. No redundant PM-localized alternate …
GLUT4 On the move
DJ Fazakerley, F Koumanov, GD Holman - Biochemical Journal, 2022 - portlandpress.com
… two exocytotic routes to the PM, one from a sequestered GLUT4 … GLUT4 exocytosis mainly
occurs through the recycling endosome route (≈20% of GLUT4), with the bulk of the GLUT4 (…
occurs through the recycling endosome route (≈20% of GLUT4), with the bulk of the GLUT4 (…
[HTML][HTML] Focus: Organelles: Glut4 storage vesicles: Specialized organelles for regulated trafficking
DT Li, EN Habtemichael, O Julca, CI Sales… - The Yale journal of …, 2019 - ncbi.nlm.nih.gov
… If GSVs are one example of a more general organelle for regulated exocytic translocation,
as we propose, then cytosolic signals similar to those on GLUT4 may be present on other …
as we propose, then cytosolic signals similar to those on GLUT4 may be present on other …
[HTML][HTML] Prior exercise in humans redistributes intramuscular GLUT4 and enhances insulin-stimulated sarcolemmal and endosomal GLUT4 translocation
JR Knudsen, DE Steenberg, JR Hingst… - Molecular …, 2020 - Elsevier
… GLUT4 to reflect a greater amount of pre-docked GLUT4 vesicles close to the T-tubuli rather
than fully inserted GLUT4 … changes in GLUT4 translocation reflect changes in exocytosis and/…
than fully inserted GLUT4 … changes in GLUT4 translocation reflect changes in exocytosis and/…
Measurement of GLUT4 traffic to and from the cell surface in muscle cells
… GLUT4 exocytosis measurements in the presence of insulin at each timepoint were normalized
to the corresponding timepoint of the basal state and shown ± SE in panel ii. Note that in …
to the corresponding timepoint of the basal state and shown ± SE in panel ii. Note that in …
Phosphorylation of Syntaxin 4 by the insulin receptor drives exocytic SNARE complex formation to deliver GLUT4 to the cell surface
D Kioumourtzoglou, HL Black, M Al Tobi, R Livingstone… - Biomolecules, 2023 - mdpi.com
… This is achieved through an increase in the exocytic trafficking rate of the facilitative glucose
transporter GLUT4 from intracellular stores to the cell surface. Delivery of GLUT4 to the cell …
transporter GLUT4 from intracellular stores to the cell surface. Delivery of GLUT4 to the cell …
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