[HTML][HTML] Low-dose acrolein, an endogenous and exogenous toxic molecule, inhibits glucose transport via an inhibition of Akt-regulated GLUT4 signaling in skeletal …

CC Wang, HJ Chen, DC Chan, CY Chiu… - International Journal of …, 2021 - mdpi.com
… in which GLUT4 is an indispensable factor [20]. The effect of acrolein on GLUT4 expression
in … As shown in Figure 1D, the protein expression of GLUT4 was significantly and markedly …

GLUT4 as A Protein Target for T2DM Therapy with Natural Compounds

VH Sutandar, MI Saleh, Z Maritska - Biology, Medicine, & Natural …, 2023 - sciencebiology.org
… in increasing GLUT4 translocation in diabetes conditions. insulin resistance state affecting
GLUT4 … in increasing the translocation of GLUT4 and helping lowering blood glucose levels. …

[HTML][HTML] Gain-of-Function Dynamin-2 Mutations Linked to Centronuclear Myopathy Impair Ca2+-Induced Exocytosis in Human Myoblasts

L Bayonés, MJ Guerra-Fernández… - International Journal of …, 2022 - mdpi.com
… Cytosolic Ca 2+ levels seem to importantly regulate exocytosis in skeletal muscle cells.
Indeed, physical exercise induces GLUT4 exocytosis in part via cytosolic Ca 2+ increments …

Following Neuropeptide Secretion: The role of SM-proteins in Dense Core Vesicle exocytosis

DC Puntman - 2022 - research.vu.nl
… not required for DCV exocytosis, or any property of DCV exocytosis including opening of the
… tested GLUT4 exocytosis marker GLUT4-pHluorin and observed GLUT4 exocytosis events …

TMF1 is upregulated by insulin and is required for a sustained glucose homeostasis

R Rahimi, I Malek, T Lerrer‐Goldshtein… - The FASEB …, 2021 - Wiley Online Library
… of GLUT4. We show that TMF1 is upregulated by insulin in myoblasts, and is essential for
the formation of insulin responsive, glucose transporter GLUT4-… GLUT4 vesicle exocytosis in …

In Vitro Reconstitution Studies of SNAREs and Their Regulators Mediating GLUT4 Vesicle Fusion

Y Liu, R He, M Zhu, H Yu - Membrane Trafficking: Methods and Protocols, 2022 - Springer
… The insulin-stimulated exocytosis of glucose transporter 4 (GLUT4 ) plays a central role …
GLUT4-containing vesicles with the plasma membrane is the last key step of GLUT4 exocytosis [1…

Regulation of the Actin Cytoskeleton by Palmitate: Implications for Lymphatic Endothelial Barrier Function and Skeletal Muscle GLUT4 Translocation

VL Tokarz - 2023 - search.proquest.com
… In Chapter 4, I outline how PA impaired GLUT4 translocation in skeletal muscle cells by …
trafficking of GLUT4. Moreover, I determined that the failure of actin remodelling and GLUT4 mis-…

[HTML][HTML] A Potential Role for GLUT4 in Predicting Sepsis in Critically Ill Children

Y Zhou, G Liu, X Wu, A Kuang, C Zhu… - Open Journal of Internal …, 2024 - scirp.org
… To the best of our knowledge, the GLUT4 protein has not been measured in the serum until
now. Moreover, the mechanism resulting in GLUT4 release in the serum remains unclear. …

[PDF][PDF] The effect of training on GLUT expression

S Huitema - 2020 - libstore.ugent.be
… Increased exocytosis leads to a higher GLUT4 concentration in the membrane. Decreased
endocytosis contributes to that higher concentration. The mitochondrial uncoupler 2,4…

Insulin And Non-Insulin Dependent Glut4 Trafficking: Regulation By The Tug Protein

S Devries - 2019 - elischolar.library.yale.edu
… Insulin releases Glut4 from static storage compartments into cycling endosomes and
increases the rate constant for Glut4 exocytosis. J Biol Chem. 2008;283(1):311-23. …