[HTML][HTML] A galantamine–curcumin hybrid decreases the cytotoxicity of amyloid-beta peptide on SH-Sy5y cells
K Mladenova, G Stavrakov, I Philipova… - International Journal of …, 2021 - mdpi.com
… and prevents apoptosis induced by β-amyloid and thapsigargin—a … GAL directly inhibits
the aggregation of Aβ peptides and … The cytotoxicity values of the AChE inhibitors tested in the …
the aggregation of Aβ peptides and … The cytotoxicity values of the AChE inhibitors tested in the …
Genistein and Galantamine Combinations Decrease β-Amyloid Peptide (1–42)–Induced Genotoxicity and Cell Death in SH-SY5Y Cell Line: an In Vitro and In Silico …
WO Castillo, NV Palomino, CS Takahashi… - Neurotoxicity …, 2020 - Springer
… that some of the AChE inhibitors such as donepezil and galantamine, and memantine, an …
cytotoxicity. The results suggest that low genistein concentrations does not cause cytotoxic …
cytotoxicity. The results suggest that low genistein concentrations does not cause cytotoxic …
[HTML][HTML] Galantamine inhibits Aβ1–42-induced neurotoxicity by enhancing α7nAChR expression as a cargo carrier for LC3 binding and Aβ1–42 engulfment during …
… binding with extracellular β-amyloid (Aβ plaques) and inhibiting Aβ-… We, therefore, evaluated
the efficacy of galantamine, a … Cell cytotoxicity of galantamine was assessed by MTT (3-(4,5-…
the efficacy of galantamine, a … Cell cytotoxicity of galantamine was assessed by MTT (3-(4,5-…
[HTML][HTML] A comparative study between lycorine and galantamine abilities to interact with AMYLOID β and reduce in vitro neurotoxicity
A Kola, S Lamponi, F Currò, D Valensin - International Journal of …, 2023 - mdpi.com
… In this research study, the ability of galantamine and lycorine … analysis and cellular cytotoxicity
assays were applied to … identify new molecules able to inhibit the aggregation of Aβ and to …
assays were applied to … identify new molecules able to inhibit the aggregation of Aβ and to …
Cassia tora prevents Aβ1-42 aggregation, inhibits acetylcholinesterase activity and protects against Aβ1-42-induced cell death and oxidative stress in human …
SK Ravi, RB Narasingappa, M Prasad… - Pharmacological …, 2019 - Elsevier
… We also analyzed the intracellular ROS level and cytotoxicity … consequence of the cleavage
of β-amyloid precursor protein (βAPP) by … 1A), while the standard AChE inhibitor galantamine …
of β-amyloid precursor protein (βAPP) by … 1A), while the standard AChE inhibitor galantamine …
[HTML][HTML] Therapeutic potential of multifunctional derivatives of cholinesterase inhibitors
M Przybyłowska, K Dzierzbicka… - Current …, 2021 - ncbi.nlm.nih.gov
… β-amyloid plaque aggregation, nitric oxide production, pro-inflammatory cytokines release,
monoamine oxidase-B activity, cytotoxicity … donepezil and galantamine hybrids which were …
monoamine oxidase-B activity, cytotoxicity … donepezil and galantamine hybrids which were …
Aminoalkyl-substituted flavonoids: synthesis, cholinesterase inhibition, β-amyloid aggregation, and neuroprotective study
… Clinically approved drugs, tacrine, donepezil, galantamine, and … of specific inhibitors
capable of inhibiting both BuChE and AChE which can also interfere with aggregation of β-amyloid …
capable of inhibiting both BuChE and AChE which can also interfere with aggregation of β-amyloid …
Neuroprotective effects of apocynin and galantamine during the chronic administration of scopolamine in an Alzheimer's disease model
E Joseph, DMÁ Villalobos-Acosta… - Journal of Molecular …, 2020 - Springer
… Cytotoxic effects were … inhibitor than galantamine. Furthermore, both molecules decreased
O 2 •- levels and NOX2 expression, with galantamine acting as a better NOX2 inhibitor than …
O 2 •- levels and NOX2 expression, with galantamine acting as a better NOX2 inhibitor than …
Effects of new galantamine derivatives in a scopolamine model of dementia in mice
M Lazarova, L Tancheva… - Journal of …, 2021 - content.iospress.com
… by stimulating the nAChR and inhibiting the Aβ- and glutamate-induced cytotoxicity [20–22] …
soluble Aβ and inhibition of the formation of Aβ plaques [23]. In fact, galantamine turns out to …
soluble Aβ and inhibition of the formation of Aβ plaques [23]. In fact, galantamine turns out to …
Synthesis of new galanthamine-peptide derivatives designed for prevention and treatment of Alzheimer's disease
LT Vezenkov, DS Tsekova… - Current Alzheimer …, 2019 - ingentaconnect.com
… All new compounds were tested in vitro for cytotoxic activity in a … galanthamine is to inhibit
the βamyloid aggregation and to … Literature data indicated that LD50 value of galantamine in …
the βamyloid aggregation and to … Literature data indicated that LD50 value of galantamine in …